Nay Michelle M, Souza Thiago L P O, Raatz Bodo, Mukankusi Clare M, Gonçalves-Vidigal Maria C, Abreu Angela F B, Melo Leonardo C, Pastor-Corrales Marcial A
ETH Zürich, Molecular Plant Breeding, Zürich, Switzerland.
EMBRAPA Arroz e Feijão, Santo Antônio de Goiás, Goiás, Brazil.
Crop Sci. 2019 Jul-Aug;59(4):1376-1391. doi: 10.2135/cropsci2018.09.0596. Epub 2019 Jun 4.
Angular leaf spot (ALS), caused by , is one of the most devastating diseases of common bean ( L.) in tropical and subtropical production areas. Breeding for ALS resistance is difficult due to the extensive virulence diversity of and the recurrent appearance of new virulent races. Five major loci, to 5, conferring ALS resistance have been named, and markers tightly linked to these loci have been reported. Quantitative trait loci (QTLs) have also been described, but the validation of some QTLs is still pending. The , , and loci are from common bean cultivars of the Andean gene pool, whereas and are from beans of the Mesoamerican gene pool. The reference genome of common bean and high-throughput sequencing technologies are enabling the development of molecular markers closely linked to the loci, more accurate mapping of the resistance loci, and the comparison of their genomic positions. The objective of this report is to provide a comprehensive review of ALS resistance in common bean. Furthermore, we are reporting three case studies of ALS resistance breeding in Latin America and Africa. This review will serve as a reference for future resistance mapping studies and as a guide for the selection of resistance loci in breeding programs aiming to develop common bean cultivars with durable ALS resistance.
角斑病（ALS）由[病原体名称缺失]引起，是热带和亚热带产区菜豆（Phaseolus vulgaris L.）最具毁灭性的病害之一。由于[病原体名称缺失]的毒力广泛多样且新的毒性小种不断出现，培育抗角斑病的品种很困难。已命名了五个赋予抗角斑病能力的主要基因座，从1到5，并报道了与这些基因座紧密连锁的标记。也描述了数量性状基因座（QTL），但一些QTL的验证仍有待完成。基因座1、2和3来自安第斯基因库的菜豆品种，而基因座4和5来自中美洲基因库的菜豆。菜豆的参考基因组和高通量测序技术有助于开发与这些基因座紧密连锁的分子标记，更精确地定位抗性基因座，并比较它们的基因组位置。本报告的目的是全面综述菜豆对角斑病的抗性。此外，我们报告了拉丁美洲和非洲抗角斑病育种的三个案例研究。本综述将为未来的抗性定位研究提供参考，并为旨在培育具有持久抗角斑病能力的菜豆品种的育种计划中抗性基因座的选择提供指导。
