Mirmohammadsadeghi Amir, Jahannama Nahid, Mirmohammadsadeghi Mohsen
Chamran Heart Center, Isfahan University of Medical Sciences (IUMS), Isfahan, Iran.
J Extra Corpor Technol. 2020 Dec;52(4):314-318. doi: 10.1182/ject-2000024.
Poor postoperative sleep quality is a common problem in patients undergoing coronary artery bypass graft surgery (CABG). The purpose of this study was to compare the effect of pulsatile and nonpulsatile pump flow on sleep quality of these patients. In this clinical trial, 52 patients undergoing on pump CABG surgery with the roller pump were randomly divided into two equal groups of 26 patients: group 1 using pulsatile pump flow and group 2 nonpulsatile pump flow while the heart was arrested. Sleep score of both groups was evaluated by Pittsburgh Sleep Quality Index questionnaire 2 days before operation and 1 month after operation, and they were compared with each other. Analysis was performed with SPSS software version 22 (SPSS for Windows Inc., Chicago, IL) using the independent -test, chi-square test, and Fisher exact test. Both groups were the same in demographic characteristics and risk factors such as age, gender, diabetes mellitus, hypertension, hyperlipidemia, smoking, body mass index, and preoperative ejection fraction. Operation data showed no difference between two groups considering cardiopulmonary bypass time and cardiac arrest time. Preoperative sleep quality score of both groups had no significant difference ( = .84). One month postoperative sleep quality score of the pulsatile group was significantly better than that of the nonpulsatile group ( = .04). Using pulsatile flow cardiopulmonary bypass can effectively decrease postoperative sleep disorders in comparison to nonpulsatile flow.
冠状动脉搭桥手术(CABG)患者术后睡眠质量差是一个常见问题。本研究的目的是比较搏动性和非搏动性泵流量对这些患者睡眠质量的影响。在这项临床试验中,52例使用滚压泵进行体外循环冠状动脉搭桥手术的患者被随机分为两组,每组26例:第1组在心脏停搏时使用搏动性泵流量,第2组使用非搏动性泵流量。两组患者在手术前2天和手术后1个月均通过匹兹堡睡眠质量指数问卷评估睡眠评分,并进行相互比较。使用SPSS 22版软件(SPSS for Windows Inc.,伊利诺伊州芝加哥)进行独立t检验、卡方检验和Fisher精确检验分析。两组在人口统计学特征和危险因素如年龄、性别、糖尿病、高血压、高脂血症、吸烟、体重指数和术前射血分数方面相同。手术数据显示,两组在体外循环时间和心脏停搏时间方面无差异。两组术前睡眠质量评分无显著差异(P = 0.84)。搏动组术后1个月的睡眠质量评分显著优于非搏动组(P = 0.04)。与非搏动流量相比,使用搏动流量体外循环可有效减少术后睡眠障碍。