Yang Yong Ryoul, Kwon Ki-Sun
Aging Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, South Korea.
Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, South Korea.
Front Physiol. 2020 Dec 3;11:602748. doi: 10.3389/fphys.2020.602748. eCollection 2020.
Regular exercise has a myriad of health benefits. An increase in circulating exercise factors following exercise is a critical physiological response. Numerous studies have shown that exercise factors released from tissues during physical activity may contribute to health benefits autocrine, paracrine, and endocrine mechanisms. Myokines, classified as proteins secreted from skeletal muscle, are representative exercise factors. The roles of myokines have been demonstrated in a variety of exercise-related functions linked to health benefits. In addition to myokines, metabolites are also exercise factors. Exercise changes the levels of various metabolites metabolic reactions. Several studies have identified exercise-induced metabolites that positively influence organ functions. Here, we provide an overview of selected metabolites secreted into the circulation upon exercise.
经常锻炼对健康有诸多益处。运动后循环运动因子的增加是一种关键的生理反应。大量研究表明，身体活动期间从组织释放的运动因子可能通过自分泌、旁分泌和内分泌机制对健康有益。肌动蛋白被归类为骨骼肌分泌的蛋白质，是具有代表性的运动因子。肌动蛋白的作用已在与健康益处相关的各种运动相关功能中得到证实。除了肌动蛋白，代谢产物也是运动因子。运动通过代谢反应改变各种代谢产物的水平。多项研究已经确定了对器官功能有积极影响的运动诱导代谢产物。在此，我们概述了运动后分泌到循环中的特定代谢产物。
