Hsieh Caleb G, Martin Jennifer L
University of California, Los Angeles.
VA Greater Los Angeles Healthcare System, University of California, Los Angeles, 16111 Plummer St #200, North Hills, CA 91343.
Curr Sleep Med Rep. 2019 Dec;5(4):234-242. doi: 10.1007/s40675-019-00157-8. Epub 2019 Nov 29.
This review summarizes key findings linking insomnia, short sleep duration, and cardiovascular health.
Early studies associations between insomnia with short sleep and cardiovascular disease Recent studies have incorporated objective data to assess sleep and identify comorbid sleep disorders (e.g. sleep apnea). Use of objective metrics has facilitated understanding of the impacts of insufficient sleep on autonomic dysregulation, metabolic syndrome, coronary artery disease and overall cardiovascular mortality. Emerging research suggests treatment of insomnia (CBT-I) may be beneficial in terms of reducing cardiovascular disease risk.
From short term effects on the autonomic nervous system to lasting effects on metabolic syndrome and coronary artery disease, there is growing evidence to support a physiologic pathway by which insomnia with short sleep contributes to cardiovascular disease. More research is needed to understand the effect of insomnia treatment on cardiovascular risk.
本综述总结了失眠、短睡眠时间与心血管健康之间联系的关键研究结果。
早期研究探讨了失眠与短睡眠和心血管疾病之间的关联。近期研究纳入了客观数据来评估睡眠并识别合并存在的睡眠障碍(如睡眠呼吸暂停)。客观指标的使用有助于理解睡眠不足对自主神经失调、代谢综合征、冠状动脉疾病及总体心血管死亡率的影响。新出现的研究表明,失眠的治疗(认知行为疗法失眠治疗)在降低心血管疾病风险方面可能有益。
从对自主神经系统的短期影响到对代谢综合征和冠状动脉疾病的长期影响,越来越多的证据支持一条生理途径,即短睡眠的失眠会导致心血管疾病。需要更多研究来了解失眠治疗对心血管风险的影响。