Silpa-Archa Sukhum, Dejkong Akkaranisorn, Kumsiang Kwanchanoke, Chotcomwongse Peranut, Preble Janine M, Foster C Stephen
Department of Ophthalmology, Faculty of Medicine, Rajavithi Hospital, Rangsit University, Bangkok 10400, Thailand.
Department of Ophthalmology Kresge Eye Institute, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.
Int J Ophthalmol. 2020 Dec 18;13(12):1968-1975. doi: 10.18240/ijo.2020.12.19. eCollection 2020.
To demonstrate prognostic factors for poor visual outcome in patients with post-traumatic endophthalmitis (PTE) following open globe injury.
A retrospective study was conducted on 66 patients (66 eyes) with PTE following open globe injury from 2005 to 2015. Potential factors accounting for good and poor visual outcome were statistically analyzed by Chi-square test and Logistic regression model.
In 66 cases, 39 cases (59%) had a poor visual outcome. Univariate and multivariate Logistic regression analysis identified retained intraocular foreign body (IOFB) as the only factor significantly associated with poor visual outcome [adjusted odds ratio, 4.62; 95% confidence interval (1.04-20.53); =0.04]. The most common causative agents were gram-positive organisms (83%), of which (33%), was the most common pathogen. All cases received intravitreal antibiotic injections. Oral ciprofloxacin was the most used systemic antibiotic (33%). Pars plana vitrectomy was performed in 83% (55/66) of cases. At 6mo follow-up, mean BCVA was 1.74±0.72 logMAR units.
In patients with PTE following open globe injury, the only predictor of poor visual outcome is the presence of IOFB. is the most isolated microorganism.
探讨开放性眼球损伤后创伤性眼内炎（PTE）患者视力预后不良的危险因素。
对2005年至2015年期间66例（66眼）开放性眼球损伤后发生PTE的患者进行回顾性研究。采用卡方检验和Logistic回归模型对影响视力预后良好和不良的潜在因素进行统计学分析。
66例患者中，39例（59%）视力预后不良。单因素和多因素Logistic回归分析确定眼内异物残留（IOFB）是与视力预后不良显著相关的唯一因素[调整优势比，4.62；95%置信区间（1.04 - 20.53）；P = 0.04]。最常见的病原体是革兰氏阳性菌（83%），其中（33%）是最常见的病原菌。所有病例均接受玻璃体内抗生素注射。口服环丙沙星是最常用的全身抗生素（33%）。83%（55/66）的病例进行了玻璃体切割术。在6个月的随访中，平均最佳矫正视力（BCVA）为1.74±0.72 LogMAR单位。
在开放性眼球损伤后发生PTE的患者中，视力预后不良的唯一预测因素是眼内异物残留。是最常见的分离微生物。
