Scorza Pamela, Monk Catherine, Lee Seonjoo, Feng Tianshu, Berry Obianuju O, Werner Elizabeth
Departments of Obstetrics and Gynecology, Columbia University, New York, NY.
Departments of Obstetrics and Gynecology, Columbia University, New York, NY; Psychiatry, Columbia University, New York, NY; New York State Psychiatric Institute, New York, NY.
Am J Obstet Gynecol MFM. 2020 Nov;2(4):100230. doi: 10.1016/j.ajogmf.2020.100230. Epub 2020 Oct 1.
The United States Preventive Services Task Force recommends that clinicians provide or refer pregnant and postpartum women who are at an increased risk of perinatal depression to counseling interventions. However, this prevention goal requires effective interventions that reach women at risk of, but before, the development of a depressive disorder.
We describe a pilot efficacy trial of a novel dyadic intervention to prevent common maternal mental health disorders, that is, Practical Resources for Effective Postpartum Parenting, in a sample of women at risk of maternal mental health disorders based on poverty status. We hypothesized that Practical Resources for Effective Postpartum Parenting compared with enhanced treatment as usual would reduce symptoms of maternal mental health disorders after birth.
A total of 60 pregnant women who were recruited from obstetrical practices at Columbia University Irving Medical Center were randomized to the Practical Resources for Effective Postpartum Parenting (n=30) or enhanced treatment as usual (n=30) intervention. The Edinburgh Postnatal Depression Scale, Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, and Patient Health Questionnaire were used to compare maternal mood at 6 weeks, 10 weeks, and 16 weeks after delivery.
At 6 weeks after delivery, women randomized to Practical Resources for Effective Postpartum Parenting had lower mean Edinburgh Postnatal Depression scores (P=.018), lower mean Hamilton Depression scores (P<.001), and lower mean Hamilton Anxiety scores (P=.041); however, the incidence of postpartum mental disorders did not differ by treatment group.
The Practical Resources for Effective Postpartum Parenting, which is an intervention integrated within obstetrical care, improves subclinical symptomology for at-risk dyads at a crucial time in the early postpartum period; however, our study did not detect reductions in the incidence of postpartum mental disorders.
美国预防服务工作组建议临床医生为有围产期抑郁症风险增加的孕妇和产后妇女提供或转介至咨询干预措施。然而,这一预防目标需要有效的干预措施,以接触到处于抑郁症发作风险但尚未发作的女性。
我们在基于贫困状况有孕产妇心理健康障碍风险的女性样本中,描述了一项预防常见孕产妇心理健康障碍的新型二元干预措施(即有效产后育儿实用资源)的试点疗效试验。我们假设,与强化常规治疗相比,有效产后育儿实用资源将减少产后母亲心理健康障碍的症状。
从哥伦比亚大学欧文医学中心的产科诊所招募的60名孕妇被随机分为有效产后育儿实用资源组(n = 30)或强化常规治疗组(n = 30)。使用爱丁堡产后抑郁量表、汉密尔顿抑郁量表、汉密尔顿焦虑量表和患者健康问卷来比较产后6周、10周和16周时的母亲情绪。
在产后6周时,随机分配到有效产后育儿实用资源组的女性的爱丁堡产后抑郁量表平均得分较低(P = 0.018),汉密尔顿抑郁量表平均得分较低(P < 0.001),汉密尔顿焦虑量表平均得分较低(P = 0.041);然而,产后精神障碍的发生率在治疗组之间没有差异。
有效产后育儿实用资源是一种整合在产科护理中的干预措施,在产后早期的关键时期改善了高危二元组的亚临床症状;然而,我们的研究未发现产后精神障碍发生率的降低。