Barbieri John S, Margolis David J
J Drugs Dermatol. 2020 Dec 1;19(12):1238-1239. doi: 10.36849/JDD.2020.5145.
For women with acne, their acne often persists into adulthood, with over 50% of women reporting acne between 20–29 years of age and over 35% of women reporting acne between 30–39 years of age.1 While mild acne can usually be managed with topical medications, moderate to severe acne often requires treatment with systemic medications such as oral antibiotics, spironolactone, and isotretinoin.2 Although oral antibiotics are the most common systemic medication prescribed for women with moderate to severe acne, spironolactone may represent a safe and effective therapeutic alternative that can decrease our reliance on oral antibiotics for the treatment of acne.3–5 However, while spironolactone use is increasing, oral antibiotics are still prescribed 3 to 5 times more often than spironolactone.3.
对于患有痤疮的女性来说，她们的痤疮往往会持续到成年期，超过50%的女性在20至29岁之间有痤疮，超过35%的女性在30至39岁之间有痤疮。虽然轻度痤疮通常可以用外用药物治疗，但中度至重度痤疮往往需要用全身性药物治疗，如口服抗生素、螺内酯和异维A酸。虽然口服抗生素是为中度至重度痤疮女性开的最常见的全身性药物，但螺内酯可能是一种安全有效的治疗选择，可以减少我们对口服抗生素治疗痤疮的依赖。然而，虽然螺内酯的使用在增加，但口服抗生素的处方频率仍然比螺内酯高3至5倍。
