Hirokawa Kumi, Fujii Yasuhito, Taniguchi Toshiyo, Takaki Jiro, Tsutsumi Akizumi
Department of Nursing, Baika Women's University, Osaka, Japan.
Department of Welfare System and Health Science, Okayama Prefectural University, Soja, Japan.
Aging Male. 2020 Dec;23(5):1545-1552. doi: 10.1080/13685538.2020.1862078. Epub 2020 Dec 21.
The purpose of the study was to investigate the association between andropause symptoms and sickness absence in Japanese male workers over 2 years.
A baseline survey asking about andropause symptoms, along with blood sampling for testosterone level, was conducted in June 2009. A total of 418 men (mean age = 52.4 years, SD = 8.6) participated and were followed through 2011. Hazard ratios (HRs) and 95% confidence intervals (CIs) for sickness absence were calculated using Cox proportional hazard models.
During the follow-up period, 31 of 35 participants who took sickness absences had physical illnesses. A higher andropause symptom score was associated with an increased risk of sickness absence. Testosterone deficiency (<350 ng/dL) was not associated with sickness absence. Among the subscales of andropause symptoms, the somatic symptom score was positively associated with sickness absence, whereas testosterone deficiency combined with high sexual symptoms was not associated with sickness absence. Results were similar when limited to sickness absence because of physical illness. No significant interaction between andropause symptoms and testosterone deficiency was found.
Non-specific andropause symptoms unrelated to testosterone deficiency were positively associated with sickness absence.
本研究旨在调查日本男性工人在两年时间里更年期症状与病假之间的关联。
2009年6月进行了一项关于更年期症状的基线调查，并采集血液样本检测睾酮水平。共有418名男性（平均年龄=52.4岁，标准差=8.6）参与，并随访至2011年。使用Cox比例风险模型计算病假的风险比（HRs）和95%置信区间（CIs）。
在随访期间，35名请病假的参与者中有31人患有身体疾病。较高的更年期症状评分与病假风险增加相关。睾酮缺乏（<350 ng/dL）与病假无关。在更年期症状的各个子量表中，躯体症状评分与病假呈正相关，而睾酮缺乏与高性症状相结合与病假无关。当仅限于因身体疾病而请病假时，结果相似。未发现更年期症状与睾酮缺乏之间存在显著相互作用。
与睾酮缺乏无关的非特异性更年期症状与病假呈正相关。
