Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland.
PLoS One. 2020 Dec 21;15(12):e0244001. doi: 10.1371/journal.pone.0244001. eCollection 2020.
SARC-F is a quick questionnaire recommended as a screening tool for sarcopenia. The aim of the study was to translate, adapt, and validate the Polish version of the SARC-F for community-dwelling older adults in Poland.
We included 160 Polish volunteers aged ≥ 60 years (44% of men). The Polish version of SARC-F was adapted following standardized forward-backward translation procedure. SARC-F was validated against the six sets of diagnostic criteria as the reference standards [developed independently by European Working Group on Sarcopenia in Older People1 (EWGSOP1), European Working Group on Sarcopenia in Older People2 (EWGSOP2), Foundation for the National Institutes of Health (FNIH) Sarcopenia Project, Asia Working Group for Sarcopenia (AWGS), the International Working Group for Sarcopenia (IWGS), and Society on Sarcopenia, Cachexia and Wasting Disorders (SCWD)].
SARC-F score ≥ 4 points was observed in 18.8% of the study population. Cronbach's alpha was 0.70. The sensitivity of SARC-F varied from 33.3% to 50.0% depending on the diagnostics criteria used, while the specificity was about 85%. Positive predictive value (PPV) was low (about 30%) for five out of six sets of the diagnostic criteria used (EWGSOP2, IWGS, AWGS, FNIH, and SCWD), while the negative predictive value (NPV) was generally high (>88%). The area under the ROC curves (AUC) was 0.652-0.728. SARC-F had the largest AUC against FNIH criteria (0.728), indicating a moderate diagnostic accuracy. Similar results were found for EWGSOP2 and IWGS criteria. The AUC values were below 0.7 for AWGS, SCWD, and EWGSOP1 criteria.
Based on the results, the Polish version of SARC-F shows excellent reliability and good internal consistency. High specificity and high NPV make SARC-F a useful tool to rule-out sarcopenia with high accuracy in community-dwelling older adults, independently of the diagnostic criteria used.
SARC-F 是一种快速问卷，被推荐作为肌少症的筛查工具。本研究的目的是将 SARC-F 的波兰语版本翻译成波兰语，并在波兰的社区居住的老年人中进行验证。
我们纳入了 160 名年龄≥60 岁的波兰志愿者（44%为男性）。根据标准的前后翻译程序对 SARC-F 的波兰语版本进行了改编。SARC-F 经过 6 组独立开发的诊断标准作为参考标准进行了验证[欧洲老年人肌少症工作组 1（EWGSOP1）、欧洲老年人肌少症工作组 2（EWGSOP2）、美国国立卫生研究院基金会（FNIH）肌少症项目、亚洲肌少症工作组（AWGS）、国际肌少症工作组（IWGS）和肌少症、恶病质和消耗性疾病协会（SCWD）]。
研究人群中 18.8%的人 SARC-F 评分≥4 分。Cronbach's alpha 为 0.70。SARC-F 的灵敏度因使用的诊断标准而异，从 33.3%到 50.0%不等，而特异性约为 85%。对于使用的 6 组诊断标准中的 5 组（EWGSOP2、IWGS、AWGS、FNIH 和 SCWD），阳性预测值（PPV）较低（约 30%），而阴性预测值（NPV）较高（>88%）。ROC 曲线下面积（AUC）为 0.652-0.728。SARC-F 对 FNIH 标准的 AUC 最大（0.728），表明具有中等诊断准确性。对 EWGSOP2 和 IWGS 标准也得到了类似的结果。AUC 值低于 AWGS、SCWD 和 EWGSOP1 标准的 0.7。
根据结果，波兰语版的 SARC-F 显示出良好的可靠性和内部一致性。高特异性和高 NPV 使得 SARC-F 成为一种有用的工具，可以在社区居住的老年人中以高准确度排除肌少症，而与使用的诊断标准无关。
