Abozeid Hassanein H, Naguib Mahmoud M
Department of Poultry Diseases, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.
Reference Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Agriculture Research Center, Giza 12618, Egypt.
Vet Sci. 2020 Dec 17;7(4):204. doi: 10.3390/vetsci7040204.
Infectious bronchitis virus (IBV) is a highly evolving avian pathogen that has increasingly imposed a negative impact on poultry industry worldwide. In the last 20 years, IBV has been continuously circulating among chicken flocks in Egypt causing huge economic losses to poultry production. Multiple IBV genotypes, namely, GI-1, GI-13, GI-16, and GI-23 have been reported in Egypt possessing different genetic and pathogenic features. Different vaccine programs are being used to control the spread of the disease in Egypt. However, the virus continues to spread and evolve where multiple IBV variants and several recombination evidence have been described. In this review, we highlight the current knowledge concerning IBV circulation, genesis, and vaccination strategies in Egypt. In addition, we analyze representative Egyptian IBV strains from an evolutionary perspective based on available data of their S1 gene. We also provide insight into the importance of surveillance programs and share our perspectives for better control of IBV circulating in Egypt.
传染性支气管炎病毒（IBV）是一种高度进化的禽类病原体，对全球家禽业的负面影响日益增大。在过去20年里，IBV一直在埃及鸡群中持续传播，给家禽生产造成了巨大经济损失。埃及已报告了多种IBV基因型，即GI-1、GI-13、GI-16和GI-23，它们具有不同的遗传和致病特征。埃及正在采用不同的疫苗接种方案来控制该病的传播。然而，病毒仍在继续传播和进化，已有多种IBV变异株及若干重组证据被描述。在本综述中，我们重点介绍了有关埃及IBV传播、起源及疫苗接种策略的现有知识。此外，我们基于埃及IBV毒株S1基因的现有数据，从进化角度分析了具有代表性的埃及IBV毒株。我们还深入探讨了监测计划的重要性，并分享了我们对更好地控制埃及境内IBV传播的看法。
