Levy L M
Department of Medicine, Godfrey Huggins School of Medicine, University of Zimbabwe, Harare.
Cancer. 1988 Jan 1;61(1):189-94. doi: 10.1002/1097-0142(19880101)61:1<189::aid-cncr2820610132>3.0.co;2-q.
A 3-year prospective study of the histologic and clinical features of patients with Hodgkin's disease presenting to the medical units in Harare, Zimbabwe, was undertaken. The histologic pattern of disease was similar to that of other African countries with mixed cellularity and lymphocyte depleted patterns prevailing (58% and 21%, respectively). Unlike most African countries, however, disease occurred most commonly in teenagers and young adults. Nutritional status was poor in just under 50% of the patients. Clinically, the extent of disease at presentation was striking, with over 90% of patients having advanced stage disease in spite of the stated duration of symptoms being moderate. The histologic and clinical findings resembled those reported from other African countries, but in certain aspects the epidemiologic pattern was intermediate between those of affluent and underprivileged communities.
对津巴布韦哈拉雷各医疗单位收治的霍奇金病患者的组织学和临床特征进行了一项为期3年的前瞻性研究。疾病的组织学模式与其他非洲国家相似，以混合细胞型和淋巴细胞消减型为主（分别占58%和21%）。然而，与大多数非洲国家不同的是，该病最常见于青少年和年轻人。近50%的患者营养状况较差。临床上，就诊时疾病的程度令人惊讶，尽管所述症状持续时间为中度，但超过90%的患者处于晚期疾病阶段。组织学和临床发现与其他非洲国家报告的相似，但在某些方面，流行病学模式介于富裕社区和贫困社区之间。
