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综合瑜伽与阿育吠陀回春疗法对轻度认知障碍老年人认知功能的疗效:非随机三臂临床试验

Efficacy of Integrated Yoga and Ayurveda Rasayana on cognitive functions in elderly with mild cognitive impairment: Non-randomized three-arm clinical trial.

作者信息

Chobe Shivaji, Patra Sanjib Kumar, Chobe Meenakshi, Metri Kashinath

机构信息

Division of Yoga and Life Sciences, Swami Vivekananda Yoga AnusandhanSamsthan (SVYASA University), #19, Eknath Bhavan, Gavipuram Circle, KG Nagar, Bengaluru, 560019, India.

Department of Yoga, Central University of Rajasthan, Bandar Sindri, NH-8, Kishangarh Ajmer, 305817, India.

出版信息

J Ayurveda Integr Med. 2022 Jan-Mar;13(1):100373. doi: 10.1016/j.jaim.2020.11.003. Epub 2020 Dec 19.

Abstract

BACKGROUND

Yoga and Ayurveda are ancient sciences which emphasize on the cure of disease and the proportion of health. Both sciences are also known to reduce the aging process and are helpful in aging-related disorders.

OBJECTIVE

This study investigates the effects of Yoga and Ayurveda Rasayana combined intervention on cognition among the elderly with mild cognitive impairment.

MATERIALS AND METHODS

Seventy-two elderly persons (average age 63.3 ± 6.44 years) received Ayurveda Rasayana (AR) (n = 23) or Integrated Yoga (IY) (n = 25) or combined (IY plus AR) intervention (n = 24) for eight weeks. AR treatment consisted of Brahmi ghrita, and IY consisted of asana, pranayama, meditation, and relaxation techniques. Executive function, verbal fluency, attention, processing speed, short-term and working memory, and learning and verbal memory were assessed at the baseline and after eight weeks.

RESULTS

Within-group analysis shows that there was a significant time main effect (p < 0.05) in all cognitive measures in the three groups (IY, AR, and IY plus AR) except Digit backward test. Bonferroni post hoc test shows a significant difference in pre to post in all variables. In the between-group analysis, there was a substantial group difference for Rey's Auditory Verbal Learning Test- hits, F (2,69) = 4.376 (P < 0.016), Rey's Auditory Verbal Learning Test-Average, F (2,69) = 4.727 (0.012), Digit backward test, F (2,69) = 5.766 (0.005) after eight weeks of intervention.

CONCLUSION

Both Ayurveda Rasayana and Integrated Yoga intervention were found effective in improving cognitive abilities among the elderly with MCI. Combined Ayurveda Rasayana and Yoga intervention significantly improved learning, attention, processing speed, and working memory compared to individual response among elderly persons with MCI.

摘要

背景

瑜伽和阿育吠陀是古老的科学,强调疾病的治愈和健康的平衡。这两种科学也被认为可以减缓衰老过程,并有助于治疗与衰老相关的疾病。

目的

本研究调查瑜伽和阿育吠陀养生法联合干预对轻度认知障碍老年人认知能力的影响。

材料与方法

72名老年人(平均年龄63.3±6.44岁)接受了为期8周的阿育吠陀养生法(AR)(n = 23)、综合瑜伽(IY)(n = 25)或联合(IY加AR)干预(n = 24)。AR治疗包括服用婆罗米酥油,IY包括体式、呼吸控制法、冥想和放松技巧。在基线和8周后评估执行功能、语言流畅性、注意力、处理速度、短期和工作记忆以及学习和语言记忆。

结果

组内分析表明,除数字倒背测试外,三组(IY、AR和IY加AR)的所有认知测量指标均存在显著的时间主效应(p < 0.05)。Bonferroni事后检验显示所有变量在干预前后存在显著差异。组间分析显示,干预8周后,在雷伊听觉词语学习测验-命中数,F(2,69) = 4.376(P < 0.016)、雷伊听觉词语学习测验-平均数,F(2,69) = 4.727(0.012)、数字倒背测试,F(2,69) = 5.766(0.005)方面存在显著的组间差异。

结论

发现阿育吠陀养生法和综合瑜伽干预均能有效提高轻度认知障碍老年人的认知能力。与轻度认知障碍老年人的个体反应相比,阿育吠陀养生法和瑜伽联合干预显著改善了学习、注意力、处理速度和工作记忆。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47cb/9034459/fa76c2cd4dd6/gr1.jpg

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