Schwartz D A, Baker E L
Harvard School of Public Health, Department of Environmental Science and Physiology, Boston.
Chest. 1988 Jan;93(1):134-7. doi: 10.1378/chest.93.1.134.
To assess the potential respiratory effects of exposure to paint products, the pulmonary function of 118 construction painters was compared to construction workers unexposed to paints (314 sheet metal workers). When compared to sheet metal workers, painters reported significant excess symptoms of cough (p less than 0.05), wheezing (p less than 0.001), and dyspnea (p less than 0.0001). Nonsmoking painters working at least 15 years in the trade had significant decrements in percent predicted forced expiratory volume in one second (%FEV1)(p less than 0.025) and in the percent predicted ratio of the forced expiratory volume in one second to the forced vital capacity (%FVC1/FVC) (p less than 0.025). Current smoking painters working less than 15 years in the trade demonstrated significant decrements in %FEV1 (p less than 0.05) and %FEV1/FVC (p less than 0.05). Restricting the analysis to painters, and controlling for smoking, we observed a significant relationship between years of exposure to paint products and airflow obstruction. Painters may be at risk for developing airflow obstruction and these changes appear to be related to the duration of exposure to paint products. Painters who smoke may be at risk of developing this obstructive process earlier than nonsmokers.
为评估接触油漆产品对呼吸系统的潜在影响，将118名建筑油漆工的肺功能与未接触油漆的建筑工人（314名钣金工）进行了比较。与钣金工相比，油漆工报告咳嗽（p<0.05）、喘息（p<0.001）和呼吸困难（p<0.0001）症状明显更多。从事该行业至少15年的不吸烟油漆工，其一秒用力呼气量预测值百分比（%FEV1）（p<0.025）和一秒用力呼气量与用力肺活量预测值之比百分比（%FVC1/FVC）（p<0.025）显著下降。从事该行业不到15年的当前吸烟油漆工，其%FEV1（p<0.05）和%FEV1/FVC（p<0.05）显著下降。将分析限定在油漆工，并对吸烟情况进行控制后，我们观察到接触油漆产品的年限与气流阻塞之间存在显著关联。油漆工可能有发生气流阻塞的风险，而且这些变化似乎与接触油漆产品的持续时间有关。吸烟的油漆工可能比不吸烟者更早面临发生这种阻塞性病变的风险。
