从 3D 回到 2D 单层胃类器官芯片。
From 3D Back to 2D Monolayer Stomach Organoids-on-a-Chip.
机构信息
Institute of Experimental Internal Medicine, Medical Faculty, Otto von Guericke University, Leipziger Straße 44, 39120 Magdeburg, Germany.
Institute for Automation Technology, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
出版信息
Trends Biotechnol. 2021 Aug;39(8):745-748. doi: 10.1016/j.tibtech.2020.11.013. Epub 2020 Dec 19.
2D monolayer gastric organoids (2DMGOs)-on-a-chip have consistent structures and can live for more than a year in culture. This state-of-the-art cell physiological system in a microfluidic device provides a way to investigate biomedically relevant, stimuli-dependent cellular responses in a variety of differentiated 2DMGOs.
2D 单层胃类器官（2DMGOs）芯片具有一致的结构，在培养中可以存活一年以上。这种最先进的微流控装置中的细胞生理系统为研究各种分化的 2DMGOs 中与生物医学相关的、受刺激依赖的细胞反应提供了一种方法。
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