小鼠主要组织相容性复合体与对镰形艾美耳球虫的免疫反应。
Murine major histocompatibility complex and immune response to Eimeria falciformis.
作者信息
Mahrt J L, Shi Y F
机构信息
Department of Zoology, University of Alberta, Edmonton, Canada.
出版信息
Infect Immun. 1988 Jan;56(1):270-1. doi: 10.1128/iai.56.1.270-271.1988.
Abstract
The genetics of the immune response to Eimeria falciformis were investigated in three inbred and six congenic strains of mice. There were significant differences among strains in oocyst production and age-related mortality from parasitic infection. Genes within the H-2 complex and also non-H-2 genes share in the immune response to eimerian infection.
摘要
在三个近交系和六个同源近交系小鼠中研究了对镰形艾美耳球虫免疫反应的遗传学。不同品系在卵囊产生以及寄生虫感染导致的与年龄相关的死亡率方面存在显著差异。H-2复合体中的基因以及非H-2基因都参与了对艾美耳球虫感染的免疫反应。
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