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Eimeria tenella infection induces local gamma interferon production and intestinal lymphocyte subpopulation changes.柔嫩艾美耳球虫感染诱导局部γ干扰素产生及肠道淋巴细胞亚群变化。
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Oral vaccination against coccidiosis: responses in strains of mice that differ in susceptibility to infection with Eimeria vermiformis.针对球虫病的口服疫苗接种：对感染蠕形艾美耳球虫易感性不同的小鼠品系的反应。
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4
Characterization of immune response to Eimeria tenella antigens in a natural immunity model with hosts which differ serologically at the B locus of the major histocompatibility complex.在主要组织相容性复合体B位点血清学不同的宿主自然免疫模型中，对柔嫩艾美耳球虫抗原免疫反应的特征分析
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Responses to vaccination in strains of mice that differ in susceptibility to coccidiosis.对球虫病易感性不同的小鼠品系接种疫苗后的反应。
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本文引用的文献

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Leishmania antigens presented by GM-CSF-derived macrophages protect susceptible mice against challenge with Leishmania major.由GM-CSF衍生的巨噬细胞呈递的利什曼原虫抗原可保护易感小鼠免受硕大利什曼原虫的攻击。
J Immunol. 1993 Jun 15;150(12):5476-83.
2
Immunity to coccidiosis: genetic influences on lymphocyte and cytokine responses to infection with Eimeria vermiformis in inbred mice.对球虫病的免疫力：近交系小鼠中基因对感染蠕形艾美耳球虫的淋巴细胞和细胞因子反应的影响
Parasite Immunol. 1993 Jan;15(1):11-9. doi: 10.1111/j.1365-3024.1993.tb00567.x.
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Susceptibility to coccidiosis: effect of strain of mouse on reproduction of Eimeria vermiformis.对球虫病的易感性：小鼠品系对蠕形艾美耳球虫繁殖的影响。
Parasitology. 1984 Feb;88 ( Pt 1):45-54. doi: 10.1017/s0031182000054330.
4
Prophylactic immunization against experimental leishmaniasis. IV. Subcutaneous immunization prevents the induction of protective immunity against fatal Leishmania major infection.实验性利什曼病的预防性免疫。IV. 皮下免疫可阻止针对致命性硕大利什曼原虫感染的保护性免疫的诱导。
J Immunol. 1985 Sep;135(3):2095-101.
5
Schistosoma japonicum: biochemistry and cytochemistry of dipeptidyl aminopeptidase-II-like activity in adults.日本血吸虫：成虫中二肽基氨肽酶-II样活性的生物化学与细胞化学
Exp Parasitol. 1985 Oct;60(2):163-70. doi: 10.1016/0014-4894(85)90019-0.
6
Mouse strain variation and effects of oocyst dose in infection of mice with Eimeria falciformis, a coccidian parasite of the large intestine.小鼠品系差异及卵囊剂量对小鼠感染大型肠道球虫寄生虫镰状艾美耳球虫的影响。
Int J Parasitol. 1985 Aug;15(4):447-52. doi: 10.1016/0020-7519(85)90032-3.
7
Eimeria tenella: effects of immunity on sporozoites within the lumen of the small intestine.柔嫩艾美耳球虫：免疫力对小肠肠腔内子孢子的影响。
Exp Parasitol. 1987 Jun;63(3):337-44. doi: 10.1016/0014-4894(87)90181-0.
8
Genetics of resistance to coccidiosis: response of inbred chicken lines to infection by Eimeria tenella and Eimeria maxima.抗球虫病的遗传学：近交系鸡对柔嫩艾美耳球虫和巨型艾美耳球虫感染的反应
Br Poult Sci. 1987 Dec;28(4):705-15. doi: 10.1080/00071668708417006.
9
Immunity to coccidiosis: adoptive transfer in NIH mice challenged with Eimeria vermiformis.球虫病免疫：用蠕虫艾美耳球虫攻击的 NIH 小鼠中的过继转移
Parasite Immunol. 1988 Jan;10(1):59-69. doi: 10.1111/j.1365-3024.1988.tb00203.x.
10
Murine major histocompatibility complex and immune response to Eimeria falciformis.小鼠主要组织相容性复合体与对镰形艾美耳球虫的免疫反应。
Infect Immun. 1988 Jan;56(1):270-1. doi: 10.1128/iai.56.1.270-271.1988.

针对实验性球虫病的免疫接种在对感染易感性不同的近交系小鼠中产生了截然不同的结果。

Immunization against experimental coccidiosis produces contrasting results in inbred mice of differing susceptibility to infection.

作者信息

Rose M E, Hesketh P, Wakelin D

机构信息

Department of Immunology and Pathology, Institute for Animal Health, Compton, Nr Newbury, Berkshire, United Kingdom.

出版信息

Infect Immun. 1994 Feb;62(2):733-7. doi: 10.1128/iai.62.2.733-737.1994.

DOI:10.1128/iai.62.2.733-737.1994
PMID:8300235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC186169/
Abstract

Pretreatment of inbred mice with intravenous and/or intraperitoneal injection of an antigen prepared from sporozoites of Eimeria vermiformis modulated the course of infection with the parasite in a manner that depended on the resistance-susceptibility phenotype of the host. Mice with a resistant background (BALB) produced more oocysts and those with a susceptible background (C57BL) produced fewer oocysts than their respective controls. The optimum conditions for producing these effects were established, and evidence is presented which suggests that the phenomenon might also apply in the target host, the chicken.

摘要

用来自微小艾美耳球虫子孢子制备的抗原对近交系小鼠进行静脉内和/或腹腔内注射预处理，可调节寄生虫感染的进程，其方式取决于宿主的抗性-易感性表型。具有抗性背景（BALB）的小鼠比其各自的对照产生更多的卵囊，而具有易感背景（C57BL）的小鼠产生的卵囊较少。确定了产生这些效应的最佳条件，并提供了证据表明该现象可能也适用于目标宿主鸡。