Kokane Arun M, Joshi Rajnish, Kotnis Ashwin, Chatterjee Anirban, Yadav Kriti, Revadi G, Joshi Ankur, Pakhare Abhijit P
Community and Family Medicine, All India Institute of Medical Sciences, Bhopal, Bhopal, Madhya Pradesh, India.
General Medicine, All India Institute of Medical Sciences, Bhopal, Bhopal, Madhya Pradesh, India.
PeerJ. 2020 Dec 10;8:e10476. doi: 10.7717/peerj.10476. eCollection 2020.
National and statewide assessment of cardiovascular risk factors needs to be conducted periodically in order to inform public health policy and prioritise allocation of funds, especially in LMICs. Although there have been studies from India which have explored the determinants of cardiovascular risk factors, they have mostly been from high epidemiological transition states. The present study assessed the determinants of cardiovascular (CVD) risk factors in a low epidemiological transition state (Madhya Pradesh) using the WHO STEPwise approach to surveillance (STEPS).
A total of 5,680 persons aged 18-69 years were selected from the state of Madhya Pradesh through multi-stage cluster random sampling. Key CVD risk factors we sought to evaluate were from behavioural (tobacco, alcohol, physical activity, diet) and biological domains (overweight or obese, Hypertension, Diabetes, and Raised serum cholesterol). Key socio-demographic factors of interest were the caste and tribe groups, and rural vs urban location, in addition to known influencers of CVD risk such as age, gender and education level.
Those belonging to the scheduled tribes were more at risk of consuming tobacco (OR 2.13 (95% CI [1.52-2.98]), and a diet with less than five servings of fruits and vegetables (OR 2.78 (95% CI [1.06-7.24]), but had had the least risk of physical inactivity (OR 0.31 (95% CI [0.02-0.54]). Residence in a rural area also reduced the odds of physical inactivity (OR 0.65 (95% CI [0.46-0.92])). Lack of formal education was a risk factor for both tobacco consumption and alcohol intake (OR 1.40 (95% CI [1.08-1.82]) for tobacco use; 1.68 (95% CI [1.14-2.49]) for alcohol intake). Those belonging to schedules tribes had much lower risk of being obese (OR 0.25; 95% CI [0.17-0.37]), but were at similar risk of all other clinical CVD risk factors as compared to other caste groups.
In the current study we explored socio-demographic determinants of behavioural and biological CVD risks, and found that in Madhya Pradesh, belonging to a scheduled tribe or living in a rural location, protects against being physically inactive or being overweight or obese. Increasing age confers a greater CVD-risk in all domains. Being a male, and lack of formal education confers a greater risk for behavioural domains, but not for most clinical risk domains. Future efforts at curbing CVDs should be therefore two pronged -a population-based strategy targeting biological risk factors, and a more focussed approach directed at those displaying risky behaviour.
为了为公共卫生政策提供信息并确定资金分配的优先顺序,尤其是在低收入和中等收入国家,需要定期对心血管危险因素进行全国性和全州范围的评估。尽管印度有研究探讨了心血管危险因素的决定因素,但这些研究大多来自高流行病学转变状态的地区。本研究采用世界卫生组织的逐步监测方法(STEPS),评估了低流行病学转变状态地区(中央邦)心血管疾病(CVD)危险因素的决定因素。
通过多阶段整群随机抽样从中央邦选取了5680名年龄在18 - 69岁之间的人。我们试图评估的主要心血管疾病危险因素来自行为领域(烟草、酒精、身体活动、饮食)和生物领域(超重或肥胖、高血压、糖尿病和血清胆固醇升高)。除了心血管疾病风险的已知影响因素如年龄、性别和教育水平外,感兴趣的主要社会人口学因素是种姓和部落群体以及农村与城市地区。
属于附表部落的人吸烟风险更高(比值比2.13(95%置信区间[1.52 - 2.98])),且摄入水果和蔬菜不足五份的饮食风险更高(比值比2.78(95%置信区间[1.06 - 7.24])),但身体活动不足的风险最低(比值比0.31(95%置信区间[0.02 - 0.54]))。居住在农村地区也降低了身体活动不足的几率(比值比0.65(95%置信区间[0.46 - 0.92]))。缺乏正规教育是吸烟和饮酒的危险因素(吸烟的比值比1.40(95%置信区间[1.08 - 1.82]);饮酒的比值比1.68(95%置信区间[1.14 - 2.49]))。属于附表部落的人肥胖风险低得多(比值比0.25;95%置信区间[0.17 - 0.37]),但与其他种姓群体相比,所有其他临床心血管疾病危险因素的风险相似。
在本研究中,我们探讨了行为和生物性心血管疾病风险的社会人口学决定因素,发现在中央邦,属于附表部落或居住在农村地区可预防身体活动不足或超重或肥胖。年龄增长在所有领域都会带来更大的心血管疾病风险。男性以及缺乏正规教育在行为领域会带来更大风险,但在大多数临床风险领域并非如此。因此,未来控制心血管疾病的努力应双管齐下——针对生物危险因素的基于人群的策略,以及针对表现出危险行为者的更有针对性的方法。