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[婴儿皮肤粘蛋白沉积症]

[Cutaneous mucinosis of infancy].

作者信息

Eholzer Lisa, Oschlies Ilske, Berneburg Mark, Karrer Sigrid

机构信息

Klinik und Poliklinik für Dermatologie, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93042, Regensburg, Deutschland.

Institut für Pathologie, Sektion Hämatopathologie und Lymphknotenregister, Universitätsklinikum Schleswig-Holstein, Kiel, Deutschland.

出版信息

Hautarzt. 2021 Sep;72(9):797-800. doi: 10.1007/s00105-020-04743-8. Epub 2020 Dec 22.

DOI:10.1007/s00105-020-04743-8
PMID:33354742
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8416887/
Abstract

Cutaneous mucinosis of infancy is a rare skin disease with just a few reported cases in the literature. We report the case of an 11-year-old boy with asymptomatic, skin-coloured papules and plaques on his right arm that had appeared 9 months prior to presentation. Histology showed a dermal and deep dermal interstitial mucin deposition and fibroblast proliferation. However, because cutaneous mucinosis of infancy is a benign disease with a good prognosis, therapy is not mandatory.

摘要

婴儿期皮肤黏蛋白沉积症是一种罕见的皮肤病，文献中仅有少数病例报道。我们报告一例11岁男孩，其右臂出现无症状的肤色丘疹和斑块，在就诊前9个月出现。组织学检查显示真皮和深部真皮间质黏蛋白沉积和成纤维细胞增生。然而，由于婴儿期皮肤黏蛋白沉积症是一种预后良好的良性疾病，并非必须进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/755e/8416887/35bc5a631de6/105_2020_4743_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/755e/8416887/5a7804dff900/105_2020_4743_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/755e/8416887/35bc5a631de6/105_2020_4743_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/755e/8416887/5a7804dff900/105_2020_4743_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/755e/8416887/35bc5a631de6/105_2020_4743_Fig2_HTML.jpg

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1
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本文引用的文献

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Long-term follow-up of a patient with congenital cutaneous mucinosis of infancy and description of a new case.
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Primary paediatric cutaneous mucinoses.
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Cutaneous mucinosis of infancy: report of a rare case and review of the literature.
Dermatol Online J. 2018 Oct 15;24(10):13030/qt75k5r526.
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Cutaneous mucinosis of infancy.婴儿皮肤黏蛋白沉积症
JAAD Case Rep. 2016 Jun 27;2(3):250-2. doi: 10.1016/j.jdcr.2016.04.005. eCollection 2016 May.
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Cutaneous Mucinosis of Infancy: A Rare Congenital Case with Coexisting Progressive, Eruptive, and Spontaneously Involuting Lesions.婴儿皮肤黏蛋白沉积症：1例罕见的先天性病例，伴有进行性、发疹性和自发性消退性病变共存
Pediatr Dermatol. 2015 Nov-Dec;32(6):e255-8. doi: 10.1111/pde.12679. Epub 2015 Oct 8.
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Congenital cutaneous mucinosis with spontaneous regression: an atypical cutaneous mucinosis of infancy?先天性皮肤黏液病伴自发性消退：一种非典型的婴儿期皮肤黏液病？
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Lupus erythematosus tumidus in childhood. Report of 3 patients.
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Cutaneous mucinosis of infancy: is it a real entity or the paediatric form of lichen myxoedematosus (papular mucinosis)?婴儿皮肤黏液水肿病：它是一种独立的疾病实体还是黏液性苔藓（丘疹性黏液水肿）的儿童形式？
Br J Dermatol. 2001 Mar;144(3):590-3. doi: 10.1046/j.1365-2133.2001.04090.x.
9
Updated classification of papular mucinosis, lichen myxedematosus, and scleromyxedema.丘疹性黏蛋白病、黏液性苔藓和硬化性黏液水肿的更新分类。
J Am Acad Dermatol. 2001 Feb;44(2):273-81. doi: 10.1067/mjd.2001.111630.
10
Cutaneous mucinosis of infancy.婴儿皮肤黏蛋白沉积症
Arch Dermatol. 1980 Feb;116(2):198-200.