Yamamura M, Valdimarsson H
Scand J Immunol. 1977;6(6-7):591-4. doi: 10.1111/j.1365-3083.1977.tb02137.x.
Using new objective methods for measuring, independently, phagcytosis and killing, it was demonstrated that Candida albicans opsonized by C3-deficient serum was ingested by not killed in vitro by human polymorphonuclear leukocytes. Killing could be induced by adding purified C3 to the C3-deficient serum. It is concluded that C3 participates directely in the intracellular process leading to phagocytic killing of C. albicans.