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Participation of C3 in intracellular killing of Candida albicans.

作者信息

Yamamura M, Valdimarsson H

出版信息

Scand J Immunol. 1977;6(6-7):591-4. doi: 10.1111/j.1365-3083.1977.tb02137.x.

DOI:10.1111/j.1365-3083.1977.tb02137.x
PMID:333549
Abstract

Using new objective methods for measuring, independently, phagcytosis and killing, it was demonstrated that Candida albicans opsonized by C3-deficient serum was ingested by not killed in vitro by human polymorphonuclear leukocytes. Killing could be induced by adding purified C3 to the C3-deficient serum. It is concluded that C3 participates directely in the intracellular process leading to phagocytic killing of C. albicans.

摘要

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