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多形核中性粒细胞碘化反应作为酵母调理作用缺陷的一种评估方法。

Polymorphonuclear neutrophil iodination response as an estimate of defective yeast opsonization.

作者信息

Roberton D M, Dhanjal N K, Levinsky R J, Mowbray J F, Turner M W

出版信息

Clin Exp Immunol. 1981 Jan;43(1):208-14.

PMID:7018758
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1537125/
Abstract

Polymorphonuclear neutrophil iodide uptake can be used as a measure of yeast opsonization and optimal assay conditions are described for the identification of sera defective in this function. The use of standard normal and defective sera permits correction of inter-assay variations resulting from the use of different cell donors. The iodination assay correlated well (r = 0.74, P less than 0.001) with a direct assay of yeast opsonization when both were used to measure this function in a panel of 72 sera. Differences in results between the two assay systems for some sera may be explained by a requirement for two different surface-associated opsonic molecules in the initiation of neutrophil metabolic activity.

摘要

多形核中性粒细胞碘摄取可作为酵母调理作用的一种衡量指标,本文描述了用于鉴定该功能缺陷血清的最佳检测条件。使用标准正常血清和缺陷血清可校正因使用不同细胞供体而导致的检测间差异。当在72份血清样本中同时使用碘摄取检测和酵母调理作用直接检测来测量该功能时,碘摄取检测与直接检测具有良好的相关性(r = 0.74,P < 0.001)。对于某些血清,两种检测系统结果的差异可能是由于中性粒细胞代谢活性启动需要两种不同的表面相关调理分子。

相似文献

1
Polymorphonuclear neutrophil iodination response as an estimate of defective yeast opsonization.多形核中性粒细胞碘化反应作为酵母调理作用缺陷的一种评估方法。
Clin Exp Immunol. 1981 Jan;43(1):208-14.
2
A study of C3b deposition on yeast surfaces by sera of known opsonic potential.一项关于已知调理素活性潜力的血清对酵母表面C3b沉积的研究。
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3
The effect of C3 levels on yeast opsonization by normal and pathological sera: identification of a complement independent opsonin.C3水平对正常和病理血清酵母调理作用的影响:补体非依赖性调理素的鉴定。
Clin Exp Immunol. 1983 Dec;54(3):793-800.
4
Opsonization of yeast by human serum IgA anti-mannan antibodies and phagocytosis by human polymorphonuclear leucocytes.人血清IgA抗甘露聚糖抗体对酵母的调理作用以及人多形核白细胞的吞噬作用。
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A new semiquantitative radiometric opsonin assay. Selective measurement of opsonizing capacity of the alternative pathway.一种新的半定量放射免疫调理素测定法。替代途径调理能力的选择性测量。
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Immunology. 1986 May;58(1):111-5.
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Yeast opsonization and phagocytosis studied by a visual assay and measurement of neutrophil chemiluminescence.通过视觉测定法和中性粒细胞化学发光测量研究酵母调理作用和吞噬作用。
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Factor affecting the in vitro assessment of opsonization: a study of the kinetics of opsonization using the technique of phagocytic chemiluminescence.影响调理作用体外评估的因素:利用吞噬化学发光技术对调理作用动力学的研究
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Yeast opsonization in newborn infants and its relationship to parental atopy.新生儿的酵母调理作用及其与父母特应性的关系。
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引用本文的文献

1
A study of C3b deposition on yeast surfaces by sera of known opsonic potential.一项关于已知调理素活性潜力的血清对酵母表面C3b沉积的研究。
Clin Exp Immunol. 1981 Nov;46(2):412-9.
2
Murine anti-lymphocyte monoclonal antibodies fail to act as opsonins for allogeneic human peripheral blood polymorphonuclear phagocytes.鼠抗淋巴细胞单克隆抗体不能作为异基因人外周血多形核吞噬细胞的调理素。
Clin Exp Immunol. 1984 Feb;55(2):444-50.
3
Evaluation of C3b/C3bi opsonization and chemiluminescence with selected yeasts and bacteria using sera of different opsonic potential.使用具有不同调理素活性的血清,对选定的酵母和细菌进行C3b/C3bi调理作用及化学发光的评估。
Immunology. 1986 May;58(1):111-5.
4
Suboptimal C3b/C3bi deposition and defective yeast opsonization. I. Evidence for the absence of essential co-factor activity.补体3b/补体3bi沉积不足及酵母调理作用缺陷。I. 缺乏关键辅助因子活性的证据。
Clin Exp Immunol. 1985 Nov;62(2):427-34.
5
The level of mannan-binding protein regulates the binding of complement-derived opsonins to mannan and zymosan at low serum concentrations.甘露聚糖结合蛋白的水平在低血清浓度下调节补体衍生调理素与甘露聚糖和酵母聚糖的结合。
Clin Exp Immunol. 1990 Feb;79(2):144-50. doi: 10.1111/j.1365-2249.1990.tb05170.x.

本文引用的文献

1
Quantitative leukocyte iodination.定量白细胞碘化
N Engl J Med. 1971 Apr 8;284(14):744-50. doi: 10.1056/NEJM197104082841402.
2
Participation of an early component of complement and Hageman factor in C3 destruction by zymosan.补体早期成分和哈格曼因子参与酵母聚糖对C3的破坏作用。
Clin Immunol Immunopathol. 1975 Jul;4(2):189-98. doi: 10.1016/0090-1229(75)90054-9.
3
Familial opsonization defect associated with fatal infantile dermatitis, infections, and histiocytosis.与致命性婴儿皮炎、感染及组织细胞增多症相关的家族性调理素缺陷。
Arch Dis Child. 1975 Apr;50(4):311-7. doi: 10.1136/adc.50.4.311.
4
Iodination by human polymorphonuclear leukocytes: a re-evaluation.人类多形核白细胞的碘化作用:重新评估
J Lab Clin Med. 1977 Mar;89(3):675-86.
5
Defective opsonization. A common immunity deficiency.调理作用缺陷。一种常见的免疫缺陷。
Arch Dis Child. 1976 Feb;51(2):91-9. doi: 10.1136/adc.51.2.91.
6
Defective yeast opsonization and C2 deficiency in atopic patients.特应性患者中存在酵母调理素缺陷和C2缺乏。
Clin Exp Immunol. 1978 Nov;34(2):253-9.
7
A rapid objective method for measuring the yeast opsonisation activity of serum.一种用于测量血清酵母调理活性的快速客观方法。
J Immunol Methods. 1978;24(3-4):251-6. doi: 10.1016/0022-1759(78)90129-1.
8
A new semiquantitative radiometric opsonin assay. Selective measurement of opsonizing capacity of the alternative pathway.一种新的半定量放射免疫调理素测定法。替代途径调理能力的选择性测量。
Immunology. 1978 Apr;34(4):689-94.
9
Participation of C3 in intracellular killing of Candida albicans.
Scand J Immunol. 1977;6(6-7):591-4. doi: 10.1111/j.1365-3083.1977.tb02137.x.
10
A defect of the alternative pathway of complement.补体替代途径缺陷。
Clin Exp Immunol. 1977 Jan;27(1):30-3.