Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Inquiry. 2020 Jan-Dec;57:46958020982925. doi: 10.1177/0046958020982925.
Thailand has a high incidence and high mortality rates of influenza. This study summarizes the evidence on economic burden or costs of influenza subsequent to the occurrence of influenza illness in the Thai population by specific characteristics such as population demographics, health conditions, healthcare facilities, and/or cost types from published literature. A systematic search was conducted in six electronic databases. All costs were extracted and adjusted to 2018 US dollar value. Out of 581 records, 11 articles (1 with macroeconomic analysis and 10 with microeconomic analyses) were included. Direct medical costs per episode for outpatients and inpatients ranged from US$4.21 to US$212.17 and from US$163.62 to US$4577.83, respectively, across distinct influenza illnesses. The overall burden of influenza was between US$31.1 and US$83.6 million per year and 50-53% of these estimates referred to lost productivity. Costs of screening for an outbreak of influenza at an 8-bed-intensive-care-unit hospital was US$38242.75 per year. Labor-sensitive sectors such as services were the most affected part of the Thai economy. High economic burden tended to occur among children and older adults with co-morbidities and to be related to complications, non-vaccinated status, and severe influenza illness. Strategies involving prevention, limit of transmission, and treatment focusing on aforementioned patients' factors, containment of hospitalization expenses and quarantine process, and assistance on labor-sensitive economy sectors are likely to reduce the economic burden of influenza. However, a research gap exists regarding knowledge about the economic burden of influenza in Thailand.
泰国流感发病率和死亡率均较高。本研究通过人口统计学特征、健康状况、医疗保健设施和/或成本类型等特定特征，总结了泰国人群流感发病后流感经济负担或成本的证据，检索了 6 个电子数据库，提取所有成本并调整为 2018 年美元值。共检索到 581 篇记录，纳入 11 篇文章（1 篇宏观经济分析和 10 篇微观经济分析）。不同流感疾病的门诊和住院患者每次发作的直接医疗费用分别为 4.21 美元至 212.17 美元和 163.62 美元至 4577.83 美元。流感的总负担为每年 3110 万至 8360 万美元，其中 50-53%的估计值与生产力损失有关。对 8 张重症监护病房医院流感暴发进行筛查的成本为每年 38242.75 美元。服务等劳动密集型部门是受泰国经济影响最大的部分。高经济负担往往发生在有合并症的儿童和老年人中，与并发症、未接种疫苗和严重流感疾病有关。涉及预防、传播限制和针对上述患者因素的治疗、控制住院费用和检疫过程以及对劳动密集型经济部门的援助的策略可能会降低流感的经济负担。然而，泰国流感经济负担的相关知识仍存在研究空白。
