Senior Professor & Head, Department of Pediatric Surgery, PGIMS, Rohtak, Haryana, India.
Senior Resident, Department of Pediatrics, PGIMS, Rohtak, India; Assistant Professor, Department of Pediatrics, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India.
Trop Doct. 2021 Apr;51(2):209-212. doi: 10.1177/0049475520973616. Epub 2020 Dec 25.
Advances in diagnostic and therapeutic interventions have improved the survival of neonates with sacrococcygeal teratoma in richer countries. These changes have not yet taken place in resource-limited settings. A retrospective analysis of neonates with sacrococcygeal teratoma operated at our centre during 1997-2016 was performed. Among 44 neonates enrolled, prenatal diagnosis of sacrococcygeal teratoma was available in 25% of pregnancies. All babies except one were born vaginally. Associated congenital malformations were seen in 20% (9/44). Types of sacrococcygeal teratoma were classified as Altman type I in 12 (27.3%), 24 (54.5%) as type II, 6 (13.6%) as type III and 2 (4.5%) as type IV. Morphologically, 77% (34/44) neonates had cystic lesions. All patients were managed successfully by total excision. Histopathology confirmed mature teratoma in 43 (97.7%). After a 12-month follow-up, no recurrence was observed. An uneventful pregnancy, absence of associated congenital anomalies, cystic morphology and a mature histology are good prognostic factors.
在资源有限的环境中，诊断和治疗干预方面的进展并没有改善骶尾部畸胎瘤新生儿的存活率。本研究回顾性分析了 1997 年至 2016 年在本中心接受手术治疗的骶尾部畸胎瘤新生儿。44 例新生儿中，25%的病例在产前诊断为骶尾部畸胎瘤。除了 1 例以外，所有婴儿均经阴道分娩。20%（9/44）的患儿合并有先天性畸形。根据 Altman 分型，骶尾部畸胎瘤分为Ⅰ型 12 例（27.3%）、Ⅱ型 24 例（54.5%）、Ⅲ型 6 例（13.6%）和Ⅳ型 2 例（4.5%）。44 例患儿中，77%（34/44）为囊性病变。所有患者均通过完全切除成功治疗。组织病理学检查证实 43 例（97.7%）为成熟性畸胎瘤。12 个月的随访中，未观察到复发。良好的预后因素包括：无并发症的妊娠、无合并先天性畸形、囊性形态和成熟的组织学特征。
