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病例报告:新生儿巨大骶尾部畸胎瘤——三例报告

Case Report: Giant sacrococcygeal teratoma in neonates-a report of three cases.

作者信息

Wu Ri Ni Letu, Nong Yimin, Wang Jinben, Liang Xiujian, Zhang Baoxin, Lin Zhenying

机构信息

Department of Pediatric Surgery, Baoan Women's and Children's Hospital, Shenzhen, China.

出版信息

Front Pediatr. 2025 Jul 22;13:1600920. doi: 10.3389/fped.2025.1600920. eCollection 2025.

DOI:10.3389/fped.2025.1600920
PMID:40766910
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12321759/
Abstract

Although most cases of neonatal sacrococcygeal teratoma are benign, some can grow into very large lesions, potentially causing high-output heart failure, massive bleeding, disseminated intravascular coagulation, and even fatal outcomes. We report three cases of giant sacrococcygeal teratomas, detailing their diagnostic and therapeutic management. We emphasize that clinicians should be prepared with comprehensive contingency plans and that interdisciplinary collaboration is essential to enhance patient survival rates and minimize potential complications.

摘要

尽管大多数新生儿骶尾部畸胎瘤病例是良性的,但有些可能会长成非常大的病变,有可能导致高输出量心力衰竭、大量出血、弥散性血管内凝血,甚至致命后果。我们报告三例巨大骶尾部畸胎瘤病例,详细阐述其诊断和治疗管理。我们强调临床医生应制定全面的应急计划,跨学科协作对于提高患者生存率和减少潜在并发症至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f6/12321759/41abf8ae5b51/fped-13-1600920-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f6/12321759/e6f2e25c8e47/fped-13-1600920-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f6/12321759/34229f924adf/fped-13-1600920-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f6/12321759/aa34398440b0/fped-13-1600920-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f6/12321759/41abf8ae5b51/fped-13-1600920-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f6/12321759/e6f2e25c8e47/fped-13-1600920-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f6/12321759/34229f924adf/fped-13-1600920-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f6/12321759/aa34398440b0/fped-13-1600920-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f6/12321759/41abf8ae5b51/fped-13-1600920-g004.jpg

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本文引用的文献

1
Fetal Sacrococcygeal Teratoma: A Case Report of a Giant Tumor withan Excellent Outcome.胎儿骶尾部畸胎瘤:一例巨大肿瘤且预后良好的病例报告
Acta Med Litu. 2023;30(2):206-215. doi: 10.15388/Amed.2023.30.2.13. Epub 2023 Jul 31.
2
Prognostic accuracy of factors associated with poor outcome in prenatally diagnosed sacrococcygeal teratoma: A systematic review and meta-analysis.产前诊断的骶尾部畸胎瘤预后不良相关因素的预后准确性:一项系统评价和荟萃分析。
Prenat Diagn. 2023 Nov;43(12):1495-1505. doi: 10.1002/pd.6457. Epub 2023 Nov 14.
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Giant sacrococcygeal teratoma in an infant: a case report with a literature review.
婴儿巨大骶尾部畸胎瘤:一例病例报告并文献复习
Ann Med Surg (Lond). 2023 Sep 7;85(11):5666-5669. doi: 10.1097/MS9.0000000000001274. eCollection 2023 Nov.
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The ex-utero intrapartum treatment (EXIT) strategy for fetal giant sacrococcygeal teratoma with cardiac insufficiency: A case report and review of the literature.胎儿巨大骶尾部畸胎瘤合并心脏功能不全的产时宫外治疗(EXIT)策略:一例病例报告及文献复习
Front Oncol. 2022 Nov 2;12:1035058. doi: 10.3389/fonc.2022.1035058. eCollection 2022.
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Sacrococcygeal Teratoma : A Tumor at the Center of Embryogenesis.骶尾部畸胎瘤:胚胎发生中心的肿瘤。
J Korean Neurosurg Soc. 2021 May;64(3):406-413. doi: 10.3340/jkns.2021.0015. Epub 2021 Apr 29.
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Clin Case Rep. 2021 Feb 13;9(3):1183-1186. doi: 10.1002/ccr3.3722. eCollection 2021 Mar.
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Neonatal sacrococcygeal teratoma: Our 20-year experience from a tertiary care centre in North India.新生儿骶尾部畸胎瘤:来自印度北部一家三级护理中心的 20 年经验。
Trop Doct. 2021 Apr;51(2):209-212. doi: 10.1177/0049475520973616. Epub 2020 Dec 25.
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Pediatr Int. 2019 Jul;61(7):672-678. doi: 10.1111/ped.13844. Epub 2019 Jun 18.
9
Hemorrhage is the most common cause of neonatal mortality in patients with sacrococcygeal teratoma.出血是骶尾部畸胎瘤患者新生儿死亡的最常见原因。
J Pediatr Surg. 2016 Nov;51(11):1826-1829. doi: 10.1016/j.jpedsurg.2016.07.005. Epub 2016 Jul 27.
10
Management of fetal teratomas.胎儿畸胎瘤的管理。
Pediatr Surg Int. 2016 Jul;32(7):635-47. doi: 10.1007/s00383-016-3892-3. Epub 2016 Apr 25.