Pozzi Ambra, Harris Raymond C
Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.
Vanderbilt Center for Kidney Disease, Vanderbilt University School of Medicine, Nashville, Tennessee.
Am J Physiol Renal Physiol. 2021 Mar 1;320(3):F342-F350. doi: 10.1152/ajprenal.00452.2020. Epub 2020 Dec 28.
The Vanderbilt O'Brien Kidney Center (VOKC) is one of the eight National Institutes of Health P30-funded centers in the United States. The mission of these core-based centers is to provide technical and conceptual support to enhance and facilitate research in the field of kidney diseases. The goal of the VOKC is to provide support to understand mechanisms and identify potential therapies for acute and chronic kidney disease. The services provided by the VOKC are meant to help the scientific community to have the right support and tools as well as to select the right animal model, statistical analysis, and clinical study design to perform innovative research and translate discoveries into personalized care to prevent, diagnose, and cure kidney disease. To achieve these goals, the VOKC has in place a program to foster collaborative investigation into critical questions of kidney disease, to personalize diagnosis and treatment of kidney disease, and to disseminate information about kidney disease and the benefits of VOKC services and research. The VOKC is complemented by state-of-the-art cores and an education and outreach program whose goals are to provide an educational platform to enhance the study of kidney disease, to publicize information about services available through the VOKC, and to provide information about kidney disease to patients and other interested members of the community. In this review, we highlight the major services and contributions of the VOKC.
范德比尔特奥布赖恩肾脏中心(VOKC)是美国国立卫生研究院资助的八个P30中心之一。这些核心中心的使命是提供技术和概念支持,以加强和促进肾脏疾病领域的研究。VOKC的目标是为理解急性和慢性肾病的机制及确定潜在治疗方法提供支持。VOKC提供的服务旨在帮助科学界获得恰当的支持和工具,以及选择合适的动物模型、统计分析和临床研究设计,以开展创新性研究并将研究成果转化为个性化医疗,从而预防、诊断和治疗肾病。为实现这些目标,VOKC制定了一项计划,促进对肾病关键问题的合作研究,实现肾病诊断和治疗的个性化,并传播有关肾病以及VOKC服务和研究益处的信息。VOKC还配备了先进的核心设施以及教育和推广计划,其目标是提供一个教育平台,以加强对肾病的研究,宣传通过VOKC可获得的服务信息,并向患者和社区其他感兴趣的成员提供有关肾病的信息。在本综述中,我们重点介绍VOKC的主要服务和贡献。