从轻度至中度 COVID-19 疾病中康复的整体医学考虑因素。
Integrative medicine considerations for convalescence from mild-to-moderate COVID-19 disease.
机构信息
University of Arizona, College of Medicine, United States; Andrew Weil Center for Integrative Medicine, United States.
University of Arizona, College of Medicine, United States; Andrew Weil Center for Integrative Medicine, United States.
出版信息
Explore (NY). 2022 Mar-Apr;18(2):140-148. doi: 10.1016/j.explore.2020.12.005. Epub 2020 Dec 23.
Abstract
The majority of individuals infected with SARS-CoV-2 have mild-to-moderate COVID-19 disease. Convalescence from mild-to-moderate (MtoM) COVID-19 disease may be supported by integrative medicine strategies. Integrative Medicine (IM) is defined as healing-oriented medicine that takes account of the whole person, including all aspects of lifestyle. Integrative medicine strategies that may support recovery from MtoM COVID-19 are proposed given their clinically studied effects in related conditions. Adoption of an anti-inflammatory diet, supplementation with vitamin D, glutathione, melatonin, Cordyceps, Astragalus and garlic have potential utility. Osteopathic manipulation, Qigong, breathing exercises and aerobic exercise may support pulmonary recovery. Stress reduction, environmental optimization, creative expression and aromatherapy can provide healing support and minimize enduring trauma. These modalities would benefit from clinical trials in people recovering from COVID-19 infection.
摘要
大多数感染 SARS-CoV-2 的个体患有轻度至中度 COVID-19 疾病。轻度至中度（MtoM）COVID-19 疾病的康復可以通过整合医学策略来支持。整合医学（IM）被定义为以治愈为导向的医学，它考虑到整个人，包括生活方式的各个方面。鉴于相关条件下对这些整合医学策略的临床研究效果，提出了这些策略可能有助于从 MtoM COVID-19 中恢復。采用抗炎饮食、补充维生素 D、谷胱甘肽、褪黑素、蛹虫草、黄芪和大蒜具有潜在的效用。整骨疗法、气功、呼吸练习和有氧运动可能有助于肺部恢復。减少压力、优化环境、创造性表达和芳香疗法可以提供治療支持并最大限度地减少持久的创伤。这些方法将受益于对 COVID-19 感染后恢復的人群进行临床试验。
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3
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