Younkin D, Delivoria-Papadopoulos M, Reivich M, Jaggi J, Obrist W
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia.
J Pediatr. 1988 Jan;112(1):104-8. doi: 10.1016/s0022-3476(88)80131-8.
Regional differences in the local cerebral metabolic rate of glucose have been reported in newborn infants. This study was performed to determine if comparable differences exist in neonatal regional cerebral blood flow (rCBF). In 21 infants, rCBF was measured with a modified xenon 133 (133Xe) clearance technique by means of eight extracranial detectors positioned over four homologous regions (frontal, parietal, temporal, and occipital). The rCBF was lowest in the frontal region, higher in the parietal region, and highest in the temporal and occipital regions. Regional differences in rCBF may be caused by regional differences in brain development and function.
据报道，新生儿存在局部脑葡萄糖代谢率的区域差异。本研究旨在确定新生儿局部脑血流量（rCBF）是否存在类似差异。对21名婴儿采用改良的氙133（133Xe）清除技术，通过置于四个同源区域（额叶、顶叶、颞叶和枕叶）上方的八个颅外探测器测量rCBF。rCBF在额叶区域最低，在顶叶区域较高，在颞叶和枕叶区域最高。rCBF的区域差异可能是由脑发育和功能的区域差异引起的。
