McPhail N, Calvin J E, Shariatmadar A, Barber G G, Scobie T K
Division of Vascular Surgery, University of Ottawa, Ontario, Canada.
J Vasc Surg. 1988 Jan;7(1):60-8.
To assess the value of exercise testing in the prediction of cardiac risk, 100 patients requiring arterial reconstructive surgery had either treadmill testing or arm ergometry before operation. Thirty-four patients then had abdominal aortic aneurysm repair, 48 had reconstructions for aortoiliac occlusive disease, and 18 had infrainguinal revascularization procedures. Cardiac complications included myocardial infarction in 10%, acute congestive failure in 5%, malignant ventricular arrhythmias in 7%, and cardiac death in 7%. Contingency table analysis showed that patients who achieved less than 85% of their predicted maximum heart rate (PMHR) during exercise testing had a complication rate of 24%, whereas patients who achieved more than 85% of PMHR had a 6% complication rate (p = 0.0396). The degree of ST segment depression during exercise testing was not a significant predictor of cardiac complications. However, patients who had a positive stress test (ST depression more than 1 mm) and achieved less than 85% of their PMHR had a complication rate of 33%, whereas patients with a positive stress test who achieved more than 85% of their PMHR had no complications (p = 0.048). Statistical analysis with a logistic regression model showed two factors to be significant. Patients who achieved a high maximum heart rate during exercise testing had a low probability of developing postoperative cardiac complications (p = 0.04), as did patients who achieved high cardiac work load maximal oxygen uptake (p = 0.03). We conclude that preoperative exercise testing is useful to predict cardiac complications after arterial reconstruction. Patients who are able to achieve more than 85% of their PMHR and a high maximal oxygen uptake represent a low-risk group.
为评估运动试验在预测心脏风险中的价值,100例需要进行动脉重建手术的患者在术前进行了平板运动试验或手臂测力计运动试验。其中34例患者随后接受了腹主动脉瘤修复术,48例接受了主-髂动脉闭塞性疾病的重建手术,18例接受了腹股沟下血管重建手术。心脏并发症包括10%的心肌梗死、5%的急性充血性心力衰竭、7%的恶性室性心律失常以及7%的心脏死亡。列联表分析显示,在运动试验中达到预测最大心率(PMHR)不足85%的患者并发症发生率为24%,而达到PMHR超过85%的患者并发症发生率为6%(p = 0.0396)。运动试验期间ST段压低程度并非心脏并发症的显著预测指标。然而,运动试验阳性(ST段压低超过1 mm)且达到PMHR不足85%的患者并发症发生率为33%,而运动试验阳性且达到PMHR超过85%的患者无并发症发生(p = 0.048)。逻辑回归模型的统计分析显示有两个因素具有显著性。在运动试验中达到较高最大心率的患者术后发生心脏并发症的概率较低(p = 0.04),达到较高心脏工作负荷最大摄氧量的患者也是如此(p = 0.03)。我们得出结论,术前运动试验有助于预测动脉重建术后的心脏并发症。能够达到PMHR超过85%且最大摄氧量较高的患者属于低风险组。