Cain W S, Gent J F, Goodspeed R B, Leonard G
John B. Pierce Foundation Laboratory, New Haven, CT 06519.
Laryngoscope. 1988 Jan;98(1):83-8. doi: 10.1288/00005537-198801000-00017.
The olfactory test administered to patients at the Connecticut Chemosensory Clinical Research Center combines stability of outcome with sensitivity to variables known to affect olfaction (age, sex). The test, which pairs an odor threshold component with an odor identification component, readily resolves differences in function between patients and controls. It reveals differences in the distribution of functioning for various probable causes (nasal/sinus disease, postupper respiratory infection, and head trauma), proves sensitive to improvements in function caused by therapeutic intervention (ethmoidectomy, steroid administration for nasal/sinus disease), and correlates with objective signs of nasal/sinus disease (visual exam, x-ray). The two components of the test agree well, though the odor identification component seems somewhat more sensitive than the threshold component as currently designed.
在康涅狄格化学感觉临床研究中心对患者进行的嗅觉测试，将结果的稳定性与对已知影响嗅觉的变量（年龄、性别）的敏感性相结合。该测试将气味阈值部分与气味识别部分相结合，能够轻松分辨患者与对照组之间的功能差异。它揭示了各种可能病因（鼻/鼻窦疾病、上呼吸道感染后、头部外伤）的功能分布差异，对治疗干预（筛窦切除术、针对鼻/鼻窦疾病的类固醇给药）引起的功能改善很敏感，并且与鼻/鼻窦疾病的客观体征（视觉检查、X光）相关。测试的两个部分一致性良好，不过按照目前的设计，气味识别部分似乎比阈值部分稍敏感一些。
