Speizer Ilene S, Xiong Khou, Mandal Mahua, Makina-Zimalirana Ndinda, Hattori Aiko, Durno Darryn
Department of Maternal and Child Health, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, USA.
MEASURE Evaluation Project, Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Open AIDS J. 2020;14:75-83. doi: 10.2174/1874613602014010075. Epub 2020 Sep 18.
Young people in KwaZulu-Natal and Mpumalanga South Africa are at high risk of HIV and other sexually transmitted infections. Programs are needed to reach these young people and change their knowledge, attitudes, and behaviors.
The objective of this study is to use cross-sectional data from grade 10 female and male learners in randomly assigned intervention and control schools to examine knowledge, attitudes, and sexual behaviors.
Participants were in grade 10 in the 2018 school year and were attending schools randomly assigned to the intervention and control arms for implementation of the Department of Basic Education's adapted life orientation curriculum that included scripted lesson plans. The study took place in two high HIV prevalence provinces in South Africa. Participants completed self-administered tablet-based surveys and female participants provided a dried blood spot for HIV testing.
Results demonstrate that two-fifths to one-half of male learners reported being sexually experienced and a quarter (KwaZulu-Natal) to a third (Mpumalanga) of the female learners reported the same. A greater percentage of learners in Mpumalanga reported consistent condom use than learners in KwaZulu-Natal. HIV prevalence among female grade 10 learners in both provinces was about 6-7%. No notable differences are observed between intervention and control school learners on the knowledge, attitudes, and behavior outcomes.
The findings demonstrate the importance of developing HIV prevention programs for young people in high HIV prevalence provinces since these young people remain at high risk for HIV and other negative outcomes.
This study has been registered at ClinicalTrials.gov. The trial registration number is: NCT04205721. The trial was retrospectively registered on December 18, 2019.
南非夸祖鲁 - 纳塔尔省和姆普马兰加省的年轻人面临感染艾滋病毒和其他性传播感染的高风险。需要开展相关项目来覆盖这些年轻人,并改变他们的知识、态度和行为。
本研究的目的是利用来自随机分配到干预组和对照组学校的十年级男女学生的横断面数据,来考察他们的知识、态度和性行为。
参与者为2018学年的十年级学生,就读于随机分配到干预组和对照组的学校,这些学校实施了基础教育部门改编的生活指导课程,其中包括脚本化的教案。该研究在南非两个艾滋病毒高流行省份进行。参与者完成了基于平板电脑的自填式调查问卷,女性参与者提供了用于艾滋病毒检测的干血斑样本。
结果显示,五分之二至二分之一的男性学习者报告有过性经历,四分之一(夸祖鲁 - 纳塔尔省)至三分之一(姆普马兰加省)的女性学习者报告有过性经历。姆普马兰加省报告始终坚持使用避孕套的学习者比例高于夸祖鲁 - 纳塔尔省。两个省份十年级女性学习者中的艾滋病毒感染率约为6 - 7%。在知识、态度和行为结果方面,干预组和对照组学校的学习者之间未观察到显著差异。
研究结果表明,为艾滋病毒高流行省份的年轻人制定艾滋病毒预防项目非常重要,因为这些年轻人仍然面临感染艾滋病毒和其他不良后果的高风险。
本研究已在ClinicalTrials.gov注册。试验注册号为:NCT04205721。该试验于2019年12月18日进行回顾性注册。