通过碘化物介导的三氟甲基苯硒酸酯的极性反转反应实现无金属亲核三氟甲基硒化反应。
Metal-free nucleophilic trifluoromethylselenolation via an iodide-mediated umpolung reactivity of trifluoromethylselenotoluenesulfonate.
作者信息
Grollier Kevin, Taponard Alexis, De Zordo-Banliat Arnaud, Magnier Emmanuel, Billard Thierry
机构信息
Institute of Chemistry and Biochemistry (ICBMS-UMR CNRS 5246), Univ Lyon, Université Lyon 1, CNRS, CPE, INSA, 43 Bd du 11 novembre 1918, 69622 Villeurbanne, France.
Université Paris-Saclay, UVSQ, CNRS, UMR 8180, Institut Lavoisier de Versailles, 78035 Versailles Cedex, France.
出版信息
Beilstein J Org Chem. 2020 Dec 10;16:3032-3037. doi: 10.3762/bjoc.16.252. eCollection 2020.
We report herein a practical method to generate CFSe (and RSe) anions from shelf-stable reagents under iodide activation. Metal-free nucleophilic trifluoromethylselenolations have been then performed with this in situ-generated anion. Perfluoroalkylselenolations have also been described.
我们在此报告一种实用方法，可在碘化物活化下由稳定的试剂生成CFSe（和RSe）阴离子。然后用这种原位生成的阴离子进行无金属亲核三氟甲基硒化反应。全氟烷基硒化反应也已得到描述。
Zotero 插件