• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

使用辛伐他汀作为根管内药物治疗牙隐裂

Management of cracked tooth using simvastatin as intracanal medicament.

作者信息

Fawzy Mohamed, Alhadainy Hatem A, Salah-Uddin Muhammad, Abdulrab Saleem

机构信息

Department of Endodonics College of Dentistry Tanta University Tanta Egypt.

Madinat Khalifa Health Center Primary Health Care Corporation Doha Qatar.

出版信息

Clin Case Rep. 2020 Sep 17;8(12):3050-3053. doi: 10.1002/ccr3.3315. eCollection 2020 Dec.

DOI:10.1002/ccr3.3315
PMID:33363877
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7752355/
Abstract

Cracked tooth syndrome is presented as pain associated with biting and sensitivity. Intracanal medication with simvastatin stimulates hard tissue formation at crack line, and the tooth was functioning on the follow-ups.

摘要

牙隐裂综合征表现为与咬合和敏感相关的疼痛。根管内使用辛伐他汀可刺激裂纹线处硬组织形成，且该牙齿在随访期间功能正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9ce/7752355/062e087e0153/CCR3-8-3050-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9ce/7752355/a6c2c03cfcc2/CCR3-8-3050-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9ce/7752355/062e087e0153/CCR3-8-3050-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9ce/7752355/a6c2c03cfcc2/CCR3-8-3050-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9ce/7752355/062e087e0153/CCR3-8-3050-g004.jpg

相似文献

1
Management of cracked tooth using simvastatin as intracanal medicament.使用辛伐他汀作为根管内药物治疗牙隐裂
Clin Case Rep. 2020 Sep 17;8(12):3050-3053. doi: 10.1002/ccr3.3315. eCollection 2020 Dec.
2
Associations of types of pain with crack-level, tooth-level and patient-level characteristics in posterior teeth with visible cracks: Findings from the National Dental Practice-Based Research Network.可见裂纹后牙的疼痛类型与裂纹水平、牙位和患者特征的关联：来自全国牙科实践为基础的研究网络的发现。
J Dent. 2018 Mar;70:67-73. doi: 10.1016/j.jdent.2017.12.014. Epub 2017 Dec 28.
3
Biting and thermal sensitivity relief of cracked tooth restored by occlusal veneer: A 12-to 24 months prospective clinical study.咬合贴面修复牙隐裂后缓解咬噬痛和冷热敏感的 12-24 个月前瞻性临床研究。
J Dent. 2023 Nov;138:104694. doi: 10.1016/j.jdent.2023.104694. Epub 2023 Sep 9.
4
Clinical applications of a quantitative light-induced fluorescent (QLF) device in the detection and management of cracked teeth: A case report.定量光诱导荧光（QLF）设备在牙隐裂检测和处理中的临床应用：病例报告。
Photodiagnosis Photodyn Ther. 2023 Sep;43:103735. doi: 10.1016/j.pdpdt.2023.103735. Epub 2023 Aug 5.
5
Biting pain reproduced by the Tooth Slooth: an aid for early diagnosis of cracked tooth.牙平滑器引发的咬合痛：一种用于隐裂牙早期诊断的辅助手段
Quintessence Int. 2019;50(1):82-87. doi: 10.3290/j.qi.a41498.
6
Symptom changes and crack progression in untreated cracked teeth: One-year findings from the National Dental Practice-Based Research Network.未经治疗的牙隐裂患者的症状变化和裂纹进展：来自国家牙科基于实践的研究网络的一年研究结果。
J Dent. 2020 Feb;93:103269. doi: 10.1016/j.jdent.2019.103269. Epub 2019 Dec 30.
7
Observable characteristics coincident with internal cracks in teeth: Findings from The National Dental Practice-Based Research Network.可观察到的牙齿内裂纹特征：来自国家牙科实践为基础的研究网络的发现。
J Am Dent Assoc. 2018 Oct;149(10):885-892.e6. doi: 10.1016/j.adaj.2018.06.013. Epub 2018 Aug 15.
8
Treatment Decision-making of Cracked Teeth: Survey of American Endodontists.隐裂牙的治疗决策：美国牙髓病学家的调查
J Contemp Dent Pract. 2019 May 1;20(5):543-547.
9
A method of crack detection based on digital image correlation for simulated cracked tooth.基于数字图像相关的模拟牙裂裂纹检测方法。
BMC Oral Health. 2021 Oct 19;21(1):539. doi: 10.1186/s12903-021-01897-2.
10
Recommended treatment of cracked teeth: Results from the National Dental Practice-Based Research Network.推荐的治疗牙裂方法：来自全国牙科以实践为基础的研究网络的研究结果。
J Prosthet Dent. 2020 Jan;123(1):71-78. doi: 10.1016/j.prosdent.2018.12.005. Epub 2019 Jun 12.

引用本文的文献

1
Evaluation of the Anti-microbial Efficacy of a Novel Endodontic Irrigant Against Enterococcus faecalis: An In Vitro Study.一种新型根管冲洗剂对粪肠球菌抗菌效果的评价：一项体外研究。
Cureus. 2023 Oct 3;15(10):e46410. doi: 10.7759/cureus.46410. eCollection 2023 Oct.
2
Management and prognosis of a vital cracked tooth by occlusal veneer for 14 months: A case report.采用咬合贴面治疗活髓隐裂牙14个月的管理与预后：一例报告
Clin Case Rep. 2023 Aug 8;11(8):e7714. doi: 10.1002/ccr3.7714. eCollection 2023 Aug.
3
Treatment of cracked teeth: A comprehensive narrative review.

本文引用的文献

1
The effects of statins on dental and oral health: a review of preclinical and clinical studies.他汀类药物对牙齿和口腔健康的影响：临床前和临床研究综述
J Transl Med. 2020 Apr 6;18(1):155. doi: 10.1186/s12967-020-02326-8.
2
The effect of statins on periodontal treatment-a systematic review with meta-analyses and meta-regression.他汀类药物对牙周治疗效果的系统评价：荟萃分析和荟萃回归。
Clin Oral Investig. 2018 Mar;22(2):671-687. doi: 10.1007/s00784-018-2354-9. Epub 2018 Feb 2.
3
Topical simvastatin gel as a novel therapeutic modality for palatal donor site wound healing following free gingival graft procedure.
牙隐裂的治疗：全面的叙述性综述。
Clin Exp Dent Res. 2022 Oct;8(5):1218-1248. doi: 10.1002/cre2.617. Epub 2022 Jul 9.
局部应用辛伐他汀凝胶作为游离龈瓣移植术后腭部供区伤口愈合的一种新型治疗方式。
Acta Odontol Scand. 2018 Apr;76(3):212-219. doi: 10.1080/00016357.2017.1403648. Epub 2017 Nov 16.
4
The Effect of Locally Delivered Statins on Treating Periodontal Intrabony Defects: A Systematic Review and Meta-Analysis.局部给予他汀类药物治疗牙周内骨缺损的效果：系统评价和荟萃分析。
J Periodontol. 2017 Apr;88(4):357-367. doi: 10.1902/jop.2016.160384. Epub 2016 Oct 21.
5
Simvastatin Promotes Dental Pulp Stem Cell-induced Coronal Pulp Regeneration in Pulpotomized Teeth.辛伐他汀促进牙髓切断术患牙中牙髓干细胞诱导的冠髓再生。
J Endod. 2016 Jul;42(7):1049-54. doi: 10.1016/j.joen.2016.03.007. Epub 2016 May 17.
6
Effect of statins with α-tricalcium phosphate on proliferation, differentiation, and mineralization of human dental pulp cells.阿托伐他汀钙与 α-磷酸三钙对人牙髓细胞增殖、分化及矿化的影响。
J Endod. 2013 Jun;39(6):806-12. doi: 10.1016/j.joen.2012.12.036. Epub 2013 Feb 13.
7
Simvastatin versus Calcium Hydroxide Direct Pulp Capping of Human Primary Molars: A Randomized Clinical Trial.辛伐他汀与人乳磨牙氢氧化钙直接盖髓术的比较：一项随机临床试验。
J Dent Res Dent Clin Dent Prospects. 2013 Winter;7(1):8-14. doi: 10.5681/joddd.2013.002. Epub 2013 Feb 21.
8
Simvastatin application to augment facial jaw bone in a dog model: pilot study.辛伐他汀在犬模型中增强颌面部骨骼的应用：初步研究。
J Periodontol. 2011 Apr;82(4):597-605. doi: 10.1902/jop.2010.100214. Epub 2010 Nov 2.
9
Simvastatin promotes odontoblastic differentiation and expression of angiogenic factors via heme oxygenase-1 in primary cultured human dental pulp cells.辛伐他汀通过血红素氧合酶-1 促进原代培养人牙髓细胞成牙本质细胞分化和血管生成因子的表达。
J Endod. 2010 Mar;36(3):447-52. doi: 10.1016/j.joen.2009.11.021. Epub 2010 Jan 25.
10
Simvastatin induces the odontogenic differentiation of human dental pulp stem cells in vitro and in vivo.辛伐他汀在体外和体内均可诱导人牙髓干细胞向牙源性分化。
J Endod. 2009 Mar;35(3):367-72. doi: 10.1016/j.joen.2008.11.024.