Lee Jung Su, Kim Ho Cheol, Park Sang Woo, So Hoon Sub, Woo Chang Yun, Choi Jong Han, Kim Sang Hyung, Kim Se Jin, Oh Yeon-Mok
Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Tuberc Respir Dis (Seoul). 2013 Jun;74(6):269-73. doi: 10.4046/trd.2013.74.6.269. Epub 2013 Jun 25.
Mucormycosis is a rare fungal disease that holds a fatal opportunistic fungal infection in diabetes mellitus, hematological malignancy, and immunocompromised host. Isolated pulmonary mucormycosis is extremely rare. Optimal therapy is a combined medical-surgical approach and a management of the patient's underlying disease. Herein, we report a case-study of isolated pulmonary mucormycosis which was being presented as multiple lung nodules in a patient with no underlying risk factors. Considering that the patient had poor pulmonary functions, we treated him with only antifungal agent rather than a combined medical-surgical approach. After treatment with antifungal agent for six months, the nodules of pulmonary mucormycosis were improved with the prominent reductions of size on the computed tomography.
毛霉病是一种罕见的真菌病,在糖尿病、血液系统恶性肿瘤和免疫功能低下的宿主中会引发致命的机会性真菌感染。孤立性肺毛霉病极为罕见。最佳治疗方法是内科与外科联合治疗以及对患者基础疾病的管理。在此,我们报告一例孤立性肺毛霉病的病例研究,该病例表现为一名无基础危险因素患者的多个肺结节。鉴于该患者肺功能较差,我们仅用抗真菌药物对其进行治疗,而非采用内科与外科联合治疗方法。在用抗真菌药物治疗六个月后,肺毛霉病的结节有所改善,计算机断层扫描显示其大小显著缩小。