Feng Xiao, Xie Xiaoyu, Song Shouyang, Chen Wenjun, Bian Hongjun, Rui Fajuan, Zhu Qiang, Ren Wanhua, Qin Chengyong, Qi Jianni
Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, P.R. China.
Department of Gastroenterology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250021, P.R. China.
Exp Ther Med. 2021 Jan;21(1):70. doi: 10.3892/etm.2020.9502. Epub 2020 Nov 25.
On December 31, 2019, the first case of a novel coronavirus infection was reported in Wuhan, China. The ongoing outbreak of the 2019 novel coronavirus (2019-nCoV) has caused immense global concern. According to the recommendations of the International Health Regulations Emergency Committee and the facts and cases that 215 other countries have also reported to date, the World Health Organization Director-General announced that the outbreak of 2019-nCoV constitutes a public health emergency of international concern and a severe threat to the human health worldwide. To date, the prevalence of the virus has continued in waves and is increasing globally. The present review briefly introduces the epidemiology of 2019-nCoV, as well as viral structural characteristics, and receptors and cells that may act after entering the body, laboratory examinations, imaging and pathological features, clinical manifestations, complications, treatment and management.
2019年12月31日，中国武汉报告了首例新型冠状病毒感染病例。2019新型冠状病毒（2019-nCoV）的持续爆发引起了全球的广泛关注。根据《国际卫生条例》突发事件委员会的建议以及迄今其他215个国家也已报告的事实和病例，世界卫生组织总干事宣布，2019-nCoV的爆发构成国际关注的突发公共卫生事件，对全球人类健康构成严重威胁。迄今为止，该病毒的流行呈波浪式持续，且在全球范围内不断增加。本综述简要介绍了2019-nCoV的流行病学、病毒结构特征、进入人体后可能起作用的受体和细胞、实验室检查、影像学和病理学特征、临床表现、并发症、治疗和管理。
