BBX11-BBX21-HY5 的正反馈环促进. 的光形态建成发育。

Institute of Plant and Food Sciences, Department of Biology, Southern University of Science and Technology, Shenzhen 518055, China.

State Key Laboratory of Protein and Plant Gene Research, Peking-Tsinghua Center for Life Sciences, School of Advanced Agriculture Sciences and School of Life Sciences, Peking University, Beijing 100871, China.

Plant Commun. 2020 Apr 16;1(5):100045. doi: 10.1016/j.xplc.2020.100045. eCollection 2020 Sep 14.

Light is the most important environmental factor affecting many aspects of plant development. In this study, we report that B-box protein 11 (BBX11) acts as a positive regulator of red light signaling. BBX11 loss-of-function mutant seedlings display significantly elongated hypocotyls under conditions of both red light and long day, whereas overexpression causes markedly shortened hypocotyls under various light states. BBX11 binds to the promoter to activate its transcription, while both BBX21 and HY5 associate with the promoter of to positively regulate its expression. Taken together, our results reveal positive feedback regulation of photomorphogenesis consisting of BBX11, BBX21, and HY5, thus substantiating a transcriptional regulatory mechanism in the response of plants to light during normal development.

光是影响植物发育诸多方面的最重要环境因素。在这项研究中，我们报告称 B 盒蛋白 11（BBX11）作为红光信号的正调控因子发挥作用。在红光和长日照条件下，BBX11 功能丧失型突变体幼苗的下胚轴显著伸长，而过表达则导致在各种光照条件下下胚轴明显缩短。BBX11 结合到启动子上激活其转录，而 BBX21 和 HY5 都与启动子结合，正向调控其表达。总之，我们的结果揭示了由 BBX11、BBX21 和 HY5 组成的光形态建成的正反馈调节，从而证实了植物在正常发育过程中对光反应的转录调控机制。