Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts, USA.
J Infect Dis. 2021 Dec 1;224(11):1945-1949. doi: 10.1093/infdis/jiaa780.
We compared vaginal microbial communities in postmenopausal black and white women.
Shotgun sequencing of vaginal swabs from postmenopausal women self-identified as black or white was compared using MiRKAT.
Vaginal community dominance by Lactobacillus crispatus or Lactobacillusgasseri was more common in 44 postmenopausal black women (n = 12, 27%) than among 44 matched white women (n = 2, 5%; P = .01). No individual taxa were significantly more abundant in either group.
We identified small overall differences in vaginal microbial communities of black and white postmenopausal women. L. crispatus dominance was more common in black women.
NCT02516202 (MsFLASH05) and NCT01418209 (MsFLASH03).
我们比较了绝经后黑人和白人女性的阴道微生物群落。
使用 MiRKAT 比较了自我认定为黑人和白人的绝经后女性阴道拭子的鸟枪法测序结果。
44 名绝经后黑人女性（n=12，27%）阴道群落以乳酸杆菌crispatus 或乳酸杆菌gasseri 为主，明显多于 44 名匹配的白人女性（n=2，5%；P=0.01）。两组中没有任何一种分类群的丰度明显更高。
我们发现绝经后黑人和白人女性阴道微生物群落存在微小的总体差异。L. crispatus 优势在黑人女性中更为常见。
NCT02516202（MsFLASH05）和 NCT01418209（MsFLASH03）。
