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估算公共和私营部门 COVID-19 诊断和治疗对美国医疗资源利用的影响。

Estimated Impact of Public and Private Sector COVID-19 Diagnostics and Treatments on US Healthcare Resource Utilization.

机构信息

Genentech, Medical Affairs, South San Francisco, CA, USA.

Roche Molecular Systems, Inc, Global Access and Health Economics, Pleasanton, CA, USA.

出版信息

Adv Ther. 2021 Feb;38(2):1212-1226. doi: 10.1007/s12325-020-01597-3. Epub 2020 Dec 26.

Abstract

INTRODUCTION

Coronavirus disease 2019 (COVID-19) has imposed a considerable burden on the United States (US) health system, with particular concern over healthcare capacity constraints.

METHODS

We modeled the impact of public and private sector contributions to developing diagnostic testing and treatments on COVID-19-related healthcare resource use.

RESULTS

We estimated that public sector contributions led to at least 30% reductions in COVID-19-related healthcare resource utilization. Private sector contributions to expanded diagnostic testing and treatments led to further reductions in mortality (- 44%), intensive care unit (ICU) and non-ICU hospital beds (- 30% and - 28%, respectively), and ventilator use (- 29%). The combination of lower diagnostic test sensitivity and proportions of patients self-isolating may exacerbate case numbers, and policies that encourage self-isolating should be considered.

CONCLUSION

While mechanisms exist to facilitate research, development, and patient access to diagnostic testing, future policies should focus on ensuring equitable patient access to both diagnostic testing and treatments that, in turn, will alleviate COVID-19-related resource constraints.

摘要

简介

2019 年冠状病毒病(COVID-19)给美国(美国)卫生系统带来了相当大的负担,特别关注医疗保健能力的限制。

方法

我们建立了模型,以评估公共和私营部门对开发诊断测试和治疗方法的贡献对 COVID-19 相关医疗资源使用的影响。

结果

我们估计,公共部门的贡献至少使 COVID-19 相关医疗资源利用率降低了 30%。私营部门对扩大诊断测试和治疗方法的贡献进一步降低了死亡率(-44%)、重症监护病房(ICU)和非 ICU 医院床位(分别为-30%和-28%)以及呼吸机的使用(-29%)。较低的诊断测试灵敏度和患者自我隔离的比例可能会使病例数量增加,应考虑鼓励自我隔离的政策。

结论

虽然存在促进研究、开发和患者获得诊断测试的机制,但未来的政策应侧重于确保患者公平获得诊断测试和治疗方法,这反过来将缓解 COVID-19 相关的资源限制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90c0/7889688/a2729e74f4fc/12325_2020_1597_Fig1_HTML.jpg

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