Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia.
PLoS One. 2020 Dec 28;15(12):e0244295. doi: 10.1371/journal.pone.0244295. eCollection 2020.
Chronic pelvic pain syndrome (CPPS) is one of the most common outpatient urological diagnoses, and its incidence is increasing. Extracorporeal shockwave therapy (ESWT) has been suggested for relieving local perineal symptoms associated with chronic prostatitis/CPPS. Despite several treatment methods, no causal or standardized treatment is available for CPPS. This study aimed to investigate the efficacy and safety profile of ESWT for the treatment of chronic non-bacterial prostatitis.
Studies were collected using four search engines (Pubmed, Cochrane, ScienceDirect, and EBSCOHost), on May 16, 2020; and assessed based on predetermined inclusion and exclusion criteria. Two reviewers performed study selection. Studies were then analyzed using Review Manager 5.3 for the meta-analysis.
Seventy-four publications were initially retrieved, and three studies were considered for both qualitative and quantitative analyses. From these studies, we found that the use of ESWT was significantly associated with decreased pain domain (mean difference: -3.93; 95% confidence interval [CI] -5.13, -2.73; p<0.001), improved urinary score (mean difference: -1.79; 95% CI -2.38, -1.21; p<0.001), improved quality of life (mean difference: -1.71; 95% CI -2.12, -1.31; p<0.001), and improved National Institutes of Health chronic prostatitis symptom index (NIH-CPSI) score (mean difference: -5.45; 95% CI -5.74, -5.16; p<0.001) after 12 weeks of treatment.
ESWT is efficacious and safe in reducing pain and improving urinary condition, NIH-CPSI score, and quality of life in patients with chronic non-bacterial prostatitis.
慢性骨盆疼痛综合征（CPPS）是最常见的门诊泌尿科诊断之一，其发病率正在上升。体外冲击波疗法（ESWT）已被建议用于缓解与慢性前列腺炎/CPPS 相关的局部会阴症状。尽管有几种治疗方法，但 CPPS 尚无因果或标准化的治疗方法。本研究旨在探讨 ESWT 治疗慢性非细菌性前列腺炎的疗效和安全性。
使用四个搜索引擎（Pubmed、Cochrane、ScienceDirect 和 EBSCOHost）于 2020 年 5 月 16 日收集研究，并根据预先确定的纳入和排除标准进行评估。两名审查员进行了研究选择。然后使用 Review Manager 5.3 对研究进行分析以进行荟萃分析。
最初检索到 74 篇文献，有 3 篇研究进行了定性和定量分析。从这些研究中，我们发现使用 ESWT 与疼痛域的降低显著相关（平均差异：-3.93；95%置信区间 [CI] -5.13，-2.73；p<0.001），尿评分改善（平均差异：-1.79；95% CI -2.38，-1.21；p<0.001），生活质量改善（平均差异：-1.71；95% CI -2.12，-1.31；p<0.001）和改善国立卫生研究院慢性前列腺炎症状指数（NIH-CPSI）评分（平均差异：-5.45；95% CI -5.74，-5.16；p<0.001）在治疗 12 周后。
ESWT 可有效且安全地减轻疼痛，并改善慢性非细菌性前列腺炎患者的尿状况、NIH-CPSI 评分和生活质量。
