Murdoch Children's Research Institute Melbourne, Melbourne, Vic., Australia.
Department of Paediatrics, University of Melbourne, Melbourne, Vic., Australia.
Pediatr Allergy Immunol. 2021 May;32(4):647-657. doi: 10.1111/pai.13443. Epub 2021 Jan 21.
Food allergy is a major public health issue with growing prevalence in the urbanized world and significant impact on the lives of allergic patients and their families. Research into the risk factors that have contributed to this increase and their underlying immune mechanisms could lead us to definitive ways for treatment and prevention of food allergy. For the time being, introduction of peanut and other allergenic foods in the diet at the time of weaning seems to be an effective way to prevent the development of food allergy. Improved diagnosis and appropriate management and support of food allergic patients are central to patient care with food immunotherapy and biologics making the transition to clinical practice. With the new available treatments, it is becoming increasingly important to include patients' and family preferences to provide a management plan tailored to their needs.
食物过敏是一个主要的公共卫生问题,在城市化世界中日渐普遍,对过敏患者及其家庭的生活产生重大影响。研究导致这种增长的风险因素及其潜在的免疫机制,可能为食物过敏的治疗和预防带来明确的方法。目前,在断奶时引入花生和其他过敏原食物似乎是预防食物过敏发展的有效方法。改善食物过敏患者的诊断和适当管理与支持,是食物免疫疗法和生物制剂过渡到临床实践的核心。随着新的治疗方法的出现,越来越有必要考虑患者和家庭的偏好,提供量身定制的管理计划。