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针灸治疗颈椎病所致颈部疼痛:一项系统评价和Meta分析方案

Acupuncture for neck pain caused by cervical spondylosis: a systematic review and meta-analysis protocol.

作者信息

Gao Zhen, Liu Gao-Feng, Zhang Jing, Ji Lai-Xi

机构信息

Acupuncture and Tuina School/The 3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Graduate Faculty, Tianjin University of Traditional Chinese Medicine, Tianjin, China.

出版信息

BMJ Open. 2020 Dec 18;10(12):e038455. doi: 10.1136/bmjopen-2020-038455.

Abstract

INTRODUCTION

Neck pain causes serious social and economic burden. Research on the use of acupuncture for managing cervical spondylosis has increased over time, with the quality of studies showing an improved trend. The present study seeks to use a systematic review approach to understand efficacy and safety of acupuncture for treatment of neck pain caused by cervical spondylosis.

METHODS AND ANALYSIS

We will search PubMed, Web of Science, Cochrane Library, Embase, China National Knowledge Infrastructure, Chinese BioMedical Literature, Wanfang database and VIP databases, from their inception to July 2020, to identify and retrieve all randomised controlled trials, describing the use of acupuncture for treatment of cervical spondylosis. Thereafter, two reviewers will independently select the studies, extract data and assess the risk of bias. Any disagreements, between them, will be resolved through a discussion with a third reviewer. Data synthesis and statistical analyses will be performed using the Revman V.5.3 software. Specifically, data will be synthesised by either fixed-effects (heterogeneity less than 50%) or random-effects models, following a heterogeneity test, with outcome measures focusing on pain intensity, functional disability, psychological improvements and adverse events. In cases where no considerable heterogeneity is detected, a meta-analysis will be conducted.

ETHICS AND DISSEMINATION

No ethical approval will be required for this study, since it does not infringe on anyone's interests. The findings will be published in a peer-reviewed journal or disseminated through conferences.

PROSPERO REGISTRATION NUMBER

CRD42020152379.

摘要

引言

颈部疼痛会造成严重的社会和经济负担。随着时间的推移,关于针灸治疗颈椎病的研究不断增加,研究质量呈上升趋势。本研究旨在采用系统评价方法,了解针灸治疗颈椎病所致颈部疼痛的疗效和安全性。

方法与分析

我们将检索PubMed、科学网、考克兰图书馆、Embase、中国知网、中国生物医学文献数据库、万方数据库和维普数据库,检索时间从各数据库建库至2020年7月,以识别和检索所有描述针灸治疗颈椎病的随机对照试验。之后,两名评价员将独立选择研究、提取数据并评估偏倚风险。他们之间的任何分歧将通过与第三位评价员讨论来解决。将使用Revman V.5.3软件进行数据合成和统计分析。具体而言,在进行异质性检验后,将采用固定效应模型(异质性小于50%)或随机效应模型合成数据,结局指标重点关注疼痛强度、功能障碍、心理改善情况和不良事件。若未检测到显著异质性,则将进行荟萃分析。

伦理与传播

本研究无需伦理批准,因为它不侵犯任何人的利益。研究结果将发表在同行评审期刊上或通过会议进行传播。

PROSPERO注册号:CRD42020152379。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f273/7751201/5d6bc15a12f2/bmjopen-2020-038455f01.jpg

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