腹部复发性滤泡树突状细胞肉瘤的多学科诊治：1 例报告。
Multidisciplinary diagnosis and treatment of recurrent follicular dendritic cell sarcoma in abdomen: A case report.
机构信息
Department of General Surgery.
Department of Dermatology.
出版信息
Medicine (Baltimore). 2020 Dec 18;99(51):e23588. doi: 10.1097/MD.0000000000023588.
RATIONALE
Follicular dendritic cell sarcoma (FDCS) is a rare malignant tumor derived from follicular dendritic cells, and is often associated with Castleman disease. Here we present a rare case of paraneoplastic pemphigus (PNP) with FDCS which required multidisciplinary approach for the diagnosis and treatment.
PATIENT CONCERNS
A 28-year-old Chinese female had FDCS recurrence, and primary clinical manifestation was PNP.
DIAGNOSES
PNP with FDCS.
INTERVENTIONS
The patient received gamma globulin infusion, took anlotinib, and underwent plasma exchange therapy.
OUTCOMES
The skin lesions recovered and there was no evidence of tumor recurrence.
LESSONS
The diagnosis and management of PNP with FDCS require close cooperation among surgeons, dermatologists, hematologists, otolaryngologists, oncologists, radiologists, pathologists, and respiratory doctors. The interesting clinical manifestations of this patient provide a multifaceted approach to the investigation of the interactions among FDCS, Castleman disease, and PNP.
背景
滤泡树突状细胞肉瘤（FDCS）是一种来源于滤泡树突状细胞的罕见恶性肿瘤，常与Castleman 病相关。本文报道了一例罕见的副肿瘤性天疱疮（PNP）合并 FDCS 病例，该病例的诊断和治疗需要多学科方法。
病例介绍
一名 28 岁的中国女性 FDCS 复发，首发临床表现为 PNP。
诊断
PNP 合并 FDCS。
干预措施
患者接受了丙种球蛋白输注、安罗替尼治疗和血浆置换治疗。
结果
皮肤病变恢复，无肿瘤复发迹象。
结论
PNP 合并 FDCS 的诊断和治疗需要外科医生、皮肤科医生、血液科医生、耳鼻喉科医生、肿瘤学家、放射科医生、病理学家和呼吸科医生之间的密切合作。该患者的有趣临床表现为研究 FDCS、Castleman 病和 PNP 之间的相互作用提供了一个多方面的方法。
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