Garcia Maria Beatriz, Gomez-Samper Andres F, Garcia Elizabeth, Peñaranda Augusto
Allergology Service, Fundacion Santa Fé de Bogotá, Bogotá, Colombia
Allergology Service, Unimeq, Bogotá, Colombia.
BMJ Case Rep. 2020 Dec 28;13(12):e236923. doi: 10.1136/bcr-2020-236923.
Food allergies to red meat, specifically to galactose-alpha-1,3-galactose (alpha-gal), a mammalian oligosaccharide, are considered to be very rare, especially in Asia and Latin America. Most of the cases reported are characterised by symptoms of delayed urticaria or anaphylaxis after the consumption of red meat. Sensitisation to red meat has been linked to the use of cetuximab or tick bites, especially from the and species. Here, we documented a case study from a Colombian male patient with symptoms of delayed urticaria and anaphylaxis with a history of tick bites in Colombia. The patient presented with IgE antibodies specific to alpha-gal, which is the most common epitope linked to red meat allergy induced by tick bites.
对红肉的食物过敏，特别是对半乳糖-α-1,3-半乳糖（α-半乳糖）这种哺乳动物寡糖的过敏，被认为非常罕见，尤其是在亚洲和拉丁美洲。报告的大多数病例的特征是食用红肉后出现迟发性荨麻疹或过敏反应症状。对红肉的致敏与使用西妥昔单抗或蜱虫叮咬有关，特别是来自[此处原文缺失蜱虫种类信息]和[此处原文缺失蜱虫种类信息]的蜱虫。在此，我们记录了一例来自哥伦比亚男性患者的病例研究，该患者有迟发性荨麻疹和过敏反应症状，且有在哥伦比亚被蜱虫叮咬的病史。患者体内出现了针对α-半乳糖的IgE抗体，α-半乳糖是与蜱虫叮咬诱发的红肉过敏相关的最常见表位。
