State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, Guangzhou 510640, China.
Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University, Guangzhou 510640, China.
Int J Mol Sci. 2020 Dec 23;22(1):86. doi: 10.3390/ijms22010086.
Long non-coding RNAs (lncRNAs) are pervasive transcripts of longer than 200 nucleotides and indiscernible coding potential. lncRNAs are implicated as key regulatory molecules in various fundamental biological processes at transcriptional, post-transcriptional, and epigenetic levels. Advances in computational and experimental approaches have identified numerous lncRNAs in plants. lncRNAs have been found to act as prime mediators in plant growth, development, and tolerance to stresses. This review summarizes the current research status of lncRNAs in planta, their classification based on genomic context, their mechanism of action, and specific bioinformatics tools and resources for their identification and characterization. Our overarching goal is to summarize recent progress on understanding the regulatory role of lncRNAs in plant developmental processes such as flowering time, reproductive growth, and abiotic stresses. We also review the role of lncRNA in nutrient stress and the ability to improve biotic stress tolerance in plants. Given the pivotal role of lncRNAs in various biological processes, their functional characterization in agriculturally essential crop plants is crucial for bridging the gap between phenotype and genotype.
长非编码 RNA（lncRNAs）是长度超过 200 个核苷酸且无明显编码潜能的普遍转录本。lncRNAs 被认为是转录水平、转录后水平和表观遗传水平等各种基本生物学过程中的关键调节分子。计算和实验方法的进步已经在植物中鉴定出了许多 lncRNAs。lncRNAs 被发现作为植物生长、发育和耐受应激的主要介质。本综述总结了 lncRNAs 在植物中的当前研究状况，基于基因组背景的分类，其作用机制，以及用于鉴定和描述它们的特定生物信息学工具和资源。我们的总体目标是总结理解 lncRNAs 在植物发育过程中（如花期、生殖生长和非生物胁迫）调节作用的最新进展。我们还回顾了 lncRNA 在营养胁迫和提高植物生物胁迫耐受性方面的作用。鉴于 lncRNAs 在各种生物学过程中的关键作用，它们在农业重要作物中的功能表征对于弥合表型和基因型之间的差距至关重要。
