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肺移植术后毛霉菌病继发急性心肌梗死

Acute myocardial infarction secondary to mucormycosis after lung transplantation.

作者信息

Naik Chetan A, Mathai Susan K, Sandkovsky Uriel S, Ausloos Kenneth A, Guileyardo Joseph M, Schwartz Gary, Mason David P, Gottlieb Robert, Grazia Todd J

机构信息

Center for Advanced Heart & Lung Diseases, Division of Pulmonary and Critical Care Medicine, Baylor University Medical Center at Dallas, Dallas, TX, USA.

Division of Infectious Diseases, Baylor University Medical Center at Dallas, Dallas, TX, USA.

出版信息

IDCases. 2020 Dec 9;23:e01019. doi: 10.1016/j.idcr.2020.e01019. eCollection 2021.

DOI:10.1016/j.idcr.2020.e01019
PMID:33376674
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7758357/
Abstract

We present a case of a 57-year-old man who underwent bilateral lung transplantation for idiopathic pulmonary fibrosis. His immediately post-operative course was complicated by fever and cardiac arrest. Despite supportive care and broad-spectrum antibiotics, he experienced continued clinical decline. Autopsy results indicated angioinvasive mucormycosis and coronary arteritis resulting in acute myocardial infarction as the cause of death.

摘要

我们报告一例57岁男性患者，因特发性肺纤维化接受了双肺移植手术。他术后即刻病程出现发热和心脏骤停等并发症。尽管给予了支持治疗和广谱抗生素治疗，他的临床状况仍持续恶化。尸检结果表明，血管侵袭性毛霉菌病和冠状动脉炎导致急性心肌梗死是其死亡原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3193/7758357/12570dd1b47c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3193/7758357/12570dd1b47c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3193/7758357/12570dd1b47c/gr1.jpg

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本文引用的文献

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Donor-derived infections: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.供体源性感染：美国移植感染病学会实践社区指南。
Clin Transplant. 2019 Sep;33(9):e13547. doi: 10.1111/ctr.13547. Epub 2019 Apr 10.
2
Emerging fungal infections in solid organ transplant recipients: Guidelines of the American Society of Transplantation Infectious Diseases Community of Practice.实体器官移植受者新发真菌感染：美国移植感染病学会实践社区指南。
Clin Transplant. 2019 Sep;33(9):e13525. doi: 10.1111/ctr.13525. Epub 2019 Apr 10.
3
Epidemiology of invasive mold infections in lung transplant recipients.
由冠状动脉毛霉菌栓塞引起的急性心肌梗死。
IDCases. 2023 Jan 9;31:e01686. doi: 10.1016/j.idcr.2023.e01686. eCollection 2023.
肺移植受者侵袭性霉菌感染的流行病学。
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Diagnosis and treatment of mucormycosis in patients with hematological malignancies: guidelines from the 3rd European Conference on Infections in Leukemia (ECIL 3).血液病患者毛霉菌病的诊断和治疗：第 3 届欧洲白血病感染会议（ECIL 3）指南。
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Invasive non-Aspergillus mold infections in transplant recipients, United States, 2001-2006.2001-2006 年美国移植受者中侵袭性非曲霉属霉菌感染。
Emerg Infect Dis. 2011 Oct;17(10):1855-64. doi: 10.3201/eid1710.110087.
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The Registry of the International Society for Heart and Lung Transplantation: Twenty-eighth Adult Lung and Heart-Lung Transplant Report--2011.国际心肺移植学会登记处：第28份成人肺移植和心肺联合移植报告——2011年
J Heart Lung Transplant. 2011 Oct;30(10):1104-22. doi: 10.1016/j.healun.2011.08.004.
7
Bacterial and fungal pneumonias after lung transplantation.肺移植后的细菌性和真菌性肺炎。
Transplant Proc. 2008 Apr;40(3):822-4. doi: 10.1016/j.transproceed.2008.02.049.
8
Donor-to-host transmission of bacterial and fungal infections in lung transplantation.肺移植中细菌和真菌感染的供体向宿主传播
Am J Transplant. 2006 Jan;6(1):178-82. doi: 10.1111/j.1600-6143.2005.01145.x.
9
Mucormycosis and entomophthoramycosis: a review of the clinical manifestations, diagnosis and treatment.毛霉病和虫霉病：临床表现、诊断与治疗综述
Clin Microbiol Infect. 2004 Mar;10 Suppl 1:31-47. doi: 10.1111/j.1470-9465.2004.00843.x.