Yang Liu, Hou Ajiao, Zhang Jiaxu, Wang Song, Man Wenjing, Yu Huan, Zheng Senwang, Wang Xuejiao, Liu Songtao, Jiang Hai
Key Laboratory of Chinese Materia Medica, Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin, China.
Front Pharmacol. 2020 Dec 8;11:602092. doi: 10.3389/fphar.2020.602092. eCollection 2020.
On January 2, 2020, The National Health Commission and the State Administration for Market Regulation listed Panacis Quinquefolii Radix (PQR) as a medicinal and food homologous product. PQR is the dry root of L., which has the functions of replenishing qi and nourishing Yin, clearing heat and producing body fluid. It is often used for qi deficiency and Yin deficiency, heat exhaustion, asthma and phlegm, dry mouth and pharynx. PQR is sweet, slightly bitter and cool in nature, and enter the heart, lung and kidney meridian exerts the remedial and hygienical effect. At present, active components such as saponins, flavonoids, fatty acids, polyalkynes, volatile oils and other nutrients such as amino acids, carbohydrates, vitamins and trace elements have been isolated from PQR. Modern pharmacological studies have shown that PQR has the effects of hypoglycemic, antihypertensive, anti fatigue, anti-oxidation, anti-tumor, immunomodulatory, neuroprotective and so on. In addition, PQR is recognized as a health care product to strengthen the body and dispel diseases. It is not only the raw material of Traditional Chinese medicine preparations, but also the treasure of dietary therapy and herbal cuisine. This study not only reviewed the botany, phytochemistry and pharmacology of PQR, but also summarized its quality control, toxicity and industrial applications for the first time. This paper not only summarizes the development status of PQR, but also analyzes the shortcomings of the current research on PQR, and puts forward the corresponding solutions, in order to provide reference for future scholars to study PQR.
2020年1月2日,国家卫生健康委员会和国家市场监督管理总局将西洋参列为药食同源产品。西洋参为五加科植物西洋参的干燥根,具有补气养阴、清热生津的功效,常用于气虚阴亏、内热、咳喘痰血、口燥咽干。西洋参味甘、微苦,性凉,归心、肺、肾经,发挥治疗和保健作用。目前,已从西洋参中分离出皂苷、黄酮、脂肪酸、多炔、挥发油等活性成分以及氨基酸、糖类、维生素、微量元素等营养成分。现代药理研究表明,西洋参具有降血糖、降血压、抗疲劳、抗氧化、抗肿瘤、免疫调节、神经保护等作用。此外,西洋参被公认为是一种强身祛病的保健品。它不仅是中药制剂的原料,也是食疗和药膳的佳品。本研究不仅综述了西洋参的植物学、植物化学和药理学,还首次总结了其质量控制、毒性和工业应用。本文不仅总结了西洋参的发展现状,还分析了目前西洋参研究存在的不足,并提出了相应的解决办法,以期为今后学者研究西洋参提供参考。