Lu Heng, Jiao Huan-Ran, Zhou Bing-Qian, Yang Guo-Hong, Wang Xiao, Zhang Xiao-Bo, Guo Lan-Ping, Liu Wei
Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences) Ji'nan 250014, China School of Pharmaceutical Sciences, Qilu University of Technology (Shandong Academy of Sciences) Ji'nan 250301, China.
College of Pharmacy, Shandong University of Traditional Chinese Medicine Ji'nan 250355, China.
Zhongguo Zhong Yao Za Zhi. 2022 Mar;47(6):1433-1437. doi: 10.19540/j.cnki.cjcmm.20211221.103.
Panacis Quinquefolii Radix is the dry root of Panax quinquefolium, which is a perennial plant of Araliaceae. The plant has a long growth cycle and serious growth barrier problem, which leads to the use of pesticides. As a result, the pesticide residues in Panacis Quinquefolii Radix are arousing great concern. This paper reviews the research findings on the investigation, detection methods, content analysis and risk assessment of pesticide residues in Panacis Quinquefolii Radix since 1993, and compares the pesticide residue limit standards of different countries and regions. The pesticide residues in Panacis Quinquefolii Radix have been changing from organochlorines with high toxicity to triazines and triazoles with low toxicity. The pesticide residues are generally low, while the pollution of pentachloronitrobenzene and other pesticides still exist. The detection method has evolved from chromatography to chromatography-mass spectrometry. There are no reports of health risks caused by pesticide residues of Panacis Quinquefolii Radix. Pesticide residue is a major factor restricting the sound development of Panacis Quinquefolii Radix industry in China. Therefore, we suggest to improve the registration of pesticides applied to the plant, popularize mature ecological planting mode and supporting technology, and strengthen the research on the risk assessment and limit standard of pesticide residue in Panacis Quinquefolii Radix.
西洋参是五加科多年生植物西洋参的干燥根。该植物生长周期长，存在严重的生长障碍问题，导致农药的使用。因此，西洋参中的农药残留引起了极大关注。本文综述了1993年以来西洋参农药残留的调查、检测方法、含量分析及风险评估等研究成果，并比较了不同国家和地区的农药残留限量标准。西洋参中的农药残留已从高毒性的有机氯类转变为低毒性的三嗪类和三唑类。农药残留总体较低，但五氯硝基苯等农药的污染仍然存在。检测方法已从色谱法发展到色谱 - 质谱联用法。尚无西洋参农药残留导致健康风险的报道。农药残留是制约我国西洋参产业健康发展的主要因素。因此，建议完善用于该植物的农药登记，推广成熟的生态种植模式及配套技术，加强西洋参农药残留风险评估及限量标准的研究。
