Rotter M, Koller W, Kundi M
Zentralbl Bakteriol Orig B. 1977 Aug;164(5-6):428-38.
Following a former suggestion (4) always to evaluate, the efficacy of procedures for Hygienic disinfection of hands in comparison with the results of a certain standard disinfection method, Ethanol, iso- and n-Propanol were tested in various concentrations and for various times of action on their usability in such a standard method. The disinfecting power was dependent upon (i) the alcohol (Ethanol less than iso-Propanol less than n-Propanol), (ii) the concentration (Ethanol: 60 less than 70 less than 80% ml/ml, iso-Propanol: 50 less than 60 less than 70, n-Propanol: 40 less than 50 less than 60 = 70) and (iii) the time of action (0,5 less than 1 less than 2 min). n-Propanol proved to be the fastest acting disinfectant. However, as standard disinfection method iso-Propanol (60% ml/ml) being used for 1 min has been proposed. Furthermore, the following results that have been obtained also in former investigations (8) could be confirmed: (i) there is no systematic difference between the release of test-bacteria from the fingertips of right and left hands of test-persons (ii). The efficacy of procedures for Hygienic disinfection of hands is besides other factors influenced by the testpersons. This factor may be eliminated by using the same testpersons for both, the disinfection procedure under investigation and the standard method. The results of both may, then, be related to each other and the efficacy of the former may be evaluated in comparison to the latter.
遵循之前的一项建议(4),即总是要评估手部卫生消毒程序的效果,并与某种标准消毒方法(乙醇、异丙醇和正丙醇)的结果进行比较,对不同浓度和不同作用时间的乙醇、异丙醇和正丙醇在这种标准方法中的可用性进行了测试。消毒能力取决于:(i)酒精(乙醇<异丙醇<正丙醇),(ii)浓度(乙醇:60%<70%<80%毫升/毫升,异丙醇:50%<60%<70%,正丙醇:40%<50%<60% = 70%)以及(iii)作用时间(0.5分钟<1分钟<2分钟)。事实证明正丙醇是作用最快的消毒剂。然而,已有人提议将1分钟内使用的60%毫升/毫升异丙醇作为标准消毒方法。此外,之前的研究(8)中也得到的以下结果可以得到证实:(i)测试人员左右手指尖上测试细菌的释放没有系统性差异;(ii)手部卫生消毒程序的效果除其他因素外还受测试人员的影响。通过对所研究的消毒程序和标准方法都使用相同的测试人员,可以消除这个因素。然后,两者的结果可以相互关联,并且可以将前者的效果与后者进行比较来评估。