Southern Marine Science and Engineering Guangdong Laboratory (Zhanjiang), Zhanjiang, China; Guangdong Key Laboratory for Research and Development of Natural Drugs, The Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang, China; The Key Lab of Zhanjiang for R&D Marine Microbial Resources in the Beibu Gulf Rim, Guangdong Medical University, Zhanjiang, China; The Marine Biomedical Research Institute of Guangdong Zhanjiang, Zhanjiang, China.
Southern Marine Science and Engineering Guangdong Laboratory (Zhanjiang), Zhanjiang, China.
Biomed Pharmacother. 2021 Mar;135:111173. doi: 10.1016/j.biopha.2020.111173. Epub 2020 Dec 28.
Imaging genomics refers to the establishment of the connection between invasive gene expression features and non-invasive imaging features. Tumor imaging genomics can not only understand the macroscopic phenotype of tumor, but also can deeply analyze the cellular and molecular characteristics of tumor tissue. In recent years, tumor imaging genomics has been a key in the field of medicine. The incidence of cancer in China has increased significantly, which is the main reason of disease death of urban residents. With the rapid development of imaging medicine, depending on imaging genomics, many experts have made remarkable achievements in tumor screening and diagnosis, prognosis evaluation, new treatment targets and understanding of tumor biological mechanism. This review analyzes the relationship between tumor radiology and gene expression, which provides a favorable direction for clinical staging, prognosis evaluation and accurate treatment of tumors.
影像组学是指建立侵袭性基因表达特征与非侵袭性影像特征之间的联系。肿瘤影像组学不仅可以了解肿瘤的宏观表型，还可以深入分析肿瘤组织的细胞和分子特征。近年来，肿瘤影像组学一直是医学领域的重点。中国癌症的发病率显著增加，这是城市居民疾病死亡的主要原因。随着影像医学的快速发展，许多专家依靠影像组学，在肿瘤筛查和诊断、预后评估、新的治疗靶点以及对肿瘤生物机制的理解方面取得了显著成就。本综述分析了肿瘤放射学与基因表达之间的关系，为肿瘤的临床分期、预后评估和精确治疗提供了有利方向。
