Eissa Fawzy, Ghanem Khaled, Al-Sisi Mahmoud
Environment and Bio-agriculture Department, Faculty of Agriculture, Al-Azhar University, 11884, Nasr city, Cairo, Egypt.
Central Laboratory of Residue analysis of Pesticides and Heavy Metals in Food, Agricultural Research Center, Dokki, Giza, Egypt.
Toxicol Rep. 2020 Mar 20;7:1640-1646. doi: 10.1016/j.toxrep.2020.03.004. eCollection 2020.
Nile tilapia () samples were collected at monthly intervals between July 2018 and June 2019 from 3 sampling sites (El-Rahawy, Sabal and Tala) situated along the Rosetta branch of the Nile, Egypt, to monitor the presence of 100 pesticides and 5 antibiotics using different extraction procedures followed by GC-MS/MS and LC-MS/MS. Potential human health risks via the consumption of contaminated fish was also assessed. Of the 72 analyzed fish muscle samples; 86% and 21% were contaminated with pesticides and antibiotics, respectively. Chlorpyrifos (ranging from < LOQ to 0.08 mg/kg) was the most frequently detected pesticide followed by DDE (ranging from < LOQ to 0.04 mg/kg) in 83 and 45% of the fish muscle samples, respectively. Nitrofurazone (ranging from 8.6 to 52 μg/kg) was the most frequently detected antibiotic, followed by nitrofurantoin (ranging from 1.1 to 2 μg/kg) and chloramphenicol (ranging from < LOQ to 0.17 μg/kg). These antibiotics were found in 12, 6 and 5% of the fish muscle samples, respectively. The spatial distribution of the detected pesticides and antibiotics in fish samples along the Rosetta branch showed that the highest mean concentrations were found in the Sabal area, followed by samples from Tala and El-Rahawy. An investigation into seasonal variations revealed that the highest mean concentrations of pesticides and antibiotics in fish samples were detected in winter and spring, respectively. According to target hazard quotient (THQ) calculations for the detected pollutants in Nile tilapia muscle, all pollutants gave THQ values lower than 1, indicating that the consumption of this fish from the study sites is unlikely to cause any detrimental effects to consumers.
2018年7月至2019年6月期间，每月从埃及尼罗河罗塞塔支流沿岸的3个采样点（埃尔-拉哈维、萨巴尔和塔拉）采集尼罗罗非鱼（）样本，采用不同的提取方法，随后通过气相色谱-串联质谱法（GC-MS/MS）和液相色谱-串联质谱法（LC-MS/MS）监测100种农药和5种抗生素的存在情况。还评估了食用受污染鱼类对人类健康的潜在风险。在72份分析的鱼肌肉样本中，分别有86%和21%被农药和抗生素污染。毒死蜱（含量范围为低于检测限至0.08毫克/千克）是最常检测到的农药，其次是滴滴伊（含量范围为低于检测限至0.04毫克/千克），分别在83%和45%的鱼肌肉样本中被检测到。呋喃西林（含量范围为8.6至52微克/千克）是最常检测到的抗生素，其次是呋喃妥因（含量范围为1.1至2微克/千克）和氯霉素（含量范围为低于检测限至0.17微克/千克）。这些抗生素分别在12%、6%和5%的鱼肌肉样本中被发现。罗塞塔支流沿线鱼类样本中检测到的农药和抗生素的空间分布表明，萨巴尔地区的平均浓度最高，其次是塔拉和埃尔-拉哈维的样本。对季节变化的调查显示，鱼类样本中农药和抗生素的平均浓度最高分别在冬季和春季被检测到。根据尼罗罗非鱼肌肉中检测到的污染物的目标危害商数（THQ）计算，所有污染物的THQ值均低于1，这表明食用研究地点的这种鱼不太可能对消费者造成任何有害影响。
