Ghuniem Mahmoud M, Gad Nermine, Tahon Mohamed A, Ryad Lamia
Ministry of Agriculture and Land Reclamation, Agricultural Research Center, Central Laboratory of Residue Analysis of Pesticides and Heavy Metals in Foods (QCAP Egypt), 7-Nadi El-said Street, Dokki, Giza 12311, Egypt.
Toxicol Rep. 2024 Sep 6;13:101724. doi: 10.1016/j.toxrep.2024.101724. eCollection 2024 Dec.
Environmental contaminants may enter seafood products either through water and sediments or via feed and feed additives or may be introduced during fish processing and storage. The study focused on the nutritional and toxicological significance of heavy metals, antibiotics, and pesticide residues in 48 fish samples collected from the Kafr-ElSheikh governorate in Egypt. Various analytical instruments are used to determine and detect heavy metals, antibiotics, and pesticides. These include Liquid Chromatography Tandem Mass Spectrometer (LC-MS/MS), Inductively Coupled Plasma Mass Spectrometer (ICP-MS), and Gas Chromatography-Mass Spectrometer (GC-MS). The following metals were discovered in fish species: arsenic (As), cadmium (Cd), cobalt (Co), copper (Cu), iron (Fe), mercury (Hg), manganese (Mn), and zinc (Zn). Each of these metals was detected 47 times. Chromium (Cr) was detected 40 times, nickel (Ni) was detected 27 times, and lead (Pb) was detected 6 times. The mean concentrations of As, Cd, Cr, Co, Cu, Fe, Ni, Mn, Hg, Pb, and Zn were determined to be 0.025, 0.02, 0.501, 0.50, 0.81, 12.56, 0.5, 0.689, 0.051, 0.031, and 5.78 mg/kg, respectively. All levels of cadmium, mercury, and lead detected in fish samples were significantly lower than the maximum permissible limits set by Egyptian and European standards. Furthermore, in this study, antibiotics and pesticide residues were found to be not detected in all analyzed fish samples. Based on the estimated daily intake and hazard quotient values, the concentration levels of metals found in fish samples seem to pose no significant threat to public health.
环境污染物可能通过水和沉积物、饲料及饲料添加剂进入海产品，也可能在鱼类加工和储存过程中被引入。该研究聚焦于从埃及卡夫尔-谢赫省采集的48份鱼类样本中重金属、抗生素和农药残留的营养及毒理学意义。使用了各种分析仪器来测定和检测重金属、抗生素及农药。这些仪器包括液相色谱串联质谱仪（LC-MS/MS）、电感耦合等离子体质谱仪（ICP-MS）和气相色谱-质谱仪（GC-MS）。在鱼类样本中发现了以下金属：砷（As）、镉（Cd）、钴（Co）、铜（Cu）、铁（Fe）、汞（Hg）、锰（Mn）和锌（Zn）。每种金属均被检测到47次。铬（Cr）被检测到40次，镍（Ni）被检测到27次，铅（Pb）被检测到6次。测定得出砷、镉、铬、钴、铜、铁镍、锰、汞、铅和锌的平均浓度分别为0.025、0.02、0.501、0.50、0.81、12.56、0.5、0.689、0.051、0.031和5.78毫克/千克。鱼类样本中检测到的所有镉、汞和铅含量均显著低于埃及和欧洲标准设定的最大允许限量。此外，在本研究中，所有分析的鱼类样本均未检测到抗生素和农药残留。根据估计的每日摄入量和危害商值，鱼类样本中发现的金属浓度水平似乎对公众健康不构成重大威胁。
