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ANCA testing: where are we now?

作者信息

Bond Milena, Fagni Filippo, Vaglio Augusto

机构信息

Department of Medicine, Rheumatology Clinic, S. Chiara Hospital, Trento, Italy.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

出版信息

Intern Emerg Med. 2021 Mar;16(2):269-271. doi: 10.1007/s11739-020-02584-w. Epub 2021 Jan 1.

DOI:10.1007/s11739-020-02584-w
PMID:33385295
Abstract
摘要

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ANCA testing: where are we now?抗中性粒细胞胞浆抗体检测：我们目前处于什么阶段？
Intern Emerg Med. 2021 Mar;16(2):269-271. doi: 10.1007/s11739-020-02584-w. Epub 2021 Jan 1.
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Antineutrophil cytoplasmic antibody (ANCA) testing: Audit from a clinical immunology laboratory.抗中性粒细胞胞浆抗体（ANCA）检测：来自临床免疫实验室的审核
Int J Rheum Dis. 2017 Jun;20(6):774-778. doi: 10.1111/1756-185X.12926. Epub 2016 Jul 26.
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Testing and reporting antineutrophil cytoplasmic antibodies (ANCA) in treated vasculitis and non-vasculitic disease.检测和报告治疗性血管炎和非血管炎疾病中的抗中性粒细胞胞浆抗体（ANCA）。
J Immunol Methods. 2018 Jul;458:1-7. doi: 10.1016/j.jim.2018.02.016. Epub 2018 Feb 24.
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Harmonization of antineutrophil cytoplasmic antibodies (ANCA) testing by reporting test result-specific likelihood ratios: position paper.通过报告特定检测结果似然比实现抗中性粒细胞胞浆抗体（ANCA）检测的标准化：立场文件
Clin Chem Lab Med. 2020 Oct 16;59(2):e35-e39. doi: 10.1515/cclm-2020-1178.
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[Laboratory diagnostics of ANCA-vasculitis].[抗中性粒细胞胞浆抗体相关性血管炎的实验室诊断]
Reumatizam. 2013;60(2):39-42.
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Clinical significance of positive anti-neutrophil cytoplasmic antibodies without evidence of anti-neutrophil cytoplasmic antibodies-associated vasculitis.无抗中性粒细胞胞浆抗体相关性血管炎证据的抗中性粒细胞胞浆抗体阳性的临床意义。
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A dual-fixed neutrophil substrate improves interpretation of antineutrophil cytoplasmic antibodies by indirect immunofluorescence.双固定中性粒细胞底物通过间接免疫荧光提高抗中性粒细胞胞浆抗体的解读。
Am J Clin Pathol. 2014 Sep;142(3):325-30. doi: 10.1309/AJCPG02FGQVAUSIU.
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Controversies in ANCA testing.抗中性粒细胞胞浆抗体检测的争议。
Cleve Clin J Med. 2012 Nov;79 Suppl 3:S7-11. doi: 10.3949/ccjm.79.s3.02.
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The value of anti-neutrophil cytoplasmic antibodies (ANCA) testing for the diagnosis of ANCA-associated vasculitis, a systematic review and meta-analysis.抗中性粒细胞胞浆抗体（ANCA）检测在诊断抗中性粒细胞胞浆抗体相关性血管炎中的价值：一项系统评价和荟萃分析。
Autoimmun Rev. 2021 Jan;20(1):102716. doi: 10.1016/j.autrev.2020.102716. Epub 2020 Nov 13.

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Diagnostic utility, disease activity, and disease phenotype correlation of serum ASCA, pANCA, and PR3-ANCA in pediatric inflammatory bowel disease.血清抗酿酒酵母抗体、抗中性粒细胞胞浆抗体和蛋白酶 3-抗中性粒细胞胞浆抗体在儿童炎症性肠病中的诊断效用、疾病活动度和疾病表型相关性。
J Pediatr (Rio J). 2024 Mar-Apr;100(2):204-211. doi: 10.1016/j.jped.2023.10.005. Epub 2023 Nov 24.

本文引用的文献

1
Clinical implications of ANCA positivity in a hospital setting: a tertiary center experience.在医院环境中抗中性粒细胞胞浆抗体阳性的临床意义：一家三级中心的经验。
Intern Emerg Med. 2021 Mar;16(2):429-436. doi: 10.1007/s11739-020-02518-6. Epub 2020 Oct 6.
2
2020 international consensus on ANCA testing beyond systemic vasculitis.2020 年系统性血管炎以外的抗中性粒细胞胞浆抗体检测国际共识。
Autoimmun Rev. 2020 Sep;19(9):102618. doi: 10.1016/j.autrev.2020.102618. Epub 2020 Jul 12.
3
Position paper: Revised 2017 international consensus on testing of ANCAs in granulomatosis with polyangiitis and microscopic polyangiitis.
立场文件：2017 年关于肉芽肿性多血管炎和显微镜下多血管炎抗中性粒细胞胞浆抗体检测的国际共识修订版。
Nat Rev Rheumatol. 2017 Nov;13(11):683-692. doi: 10.1038/nrrheum.2017.140. Epub 2017 Sep 14.
4
Infections and antineutrophil cytoplasmic antibodies: triggering mechanisms.感染与抗中性粒细胞胞浆抗体：触发机制。
Autoimmun Rev. 2015 Mar;14(3):201-3. doi: 10.1016/j.autrev.2014.10.020. Epub 2014 Nov 4.
5
Proteinase-3 antineutrophil cytoplasm antibody positivity in patients without primary systemic vasculitis.蛋白酶 3 抗中性粒细胞胞质抗体阳性而无原发性系统性血管炎。
J Clin Rheumatol. 2012 Oct;18(7):336-40. doi: 10.1097/RHU.0b013e31826d2005.
6
Contaminated cocaine and antineutrophil cytoplasmic antibody-associated disease.被污染的可卡因和抗中性粒细胞胞质抗体相关性疾病。
Clin J Am Soc Nephrol. 2011 Dec;6(12):2799-805. doi: 10.2215/CJN.03440411. Epub 2011 Oct 6.
7
Does a gating policy for ANCA overlook patients with ANCA associated vasculitis? An audit of 263 patients.对于抗中性粒细胞胞浆抗体（ANCA）相关性血管炎患者，采用门控策略是否会忽视这些患者？一项对 263 例患者的审计。
J Clin Pathol. 2010 Aug;63(8):678-80. doi: 10.1136/jcp.2009.072504.
8
The effect of a symptom related "gating policy" on ANCA requests in routine clinical practice.症状相关“把关政策”对常规临床实践中抗中性粒细胞胞浆抗体（ANCA）检测申请的影响。
J Clin Pathol. 2004 Feb;57(2):131-4. doi: 10.1136/jcp.2003.8052.
9
Using antineutrophil cytoplasmic antibody testing to diagnose vasculitis: can test-ordering guidelines improve diagnostic accuracy?
Arch Intern Med. 2002 Jul 8;162(13):1509-14. doi: 10.1001/archinte.162.13.1509.
10
International Consensus Statement on Testing and Reporting of Antineutrophil Cytoplasmic Antibodies (ANCA).抗中性粒细胞胞浆抗体（ANCA）检测与报告的国际共识声明。
Am J Clin Pathol. 1999 Apr;111(4):507-13. doi: 10.1093/ajcp/111.4.507.